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Creon Corporation plc (AMED)

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Friday 31 October, 2008

Creon Corporation plc

TR-1: Notifications of Major Interests in Shares


TR-1: Notifications of Major Interests in Shares                               

1. Identity of the issuer or the underlying       
issuer of existing shares to which voting rights                               
are attached: Creon Corporation Plc                                                                         
                                                                               
2. Reason for notification (yes/no)                                            
                                                                               
An acquisition or disposal of voting rights: Yes        
                                                                               
An acquisition or disposal of financial instruments which may                  
result in the acquisition of shares already issued to which voting             
rights are attached                                                            
                                                                               
An event changing the breakdown of voting rights                               
                                                                               
Other (please specify):______________                                          
                                                                               
3. Full name of person(s) subject to       
notification obligation: Singer Capital Markets Ltd                                                                
                                                                               
4. Full name of shareholder(s) (if         
different from 3): New Street Nominees Ltd                                                                         
                                                                               
5. Date of transaction (and date on which  
the threshold is crossed or reached if                                         
different): 06.10.2008                                                                                             
                                                                               
6. Date on which issuer notified: 30.10.2008                          
                                                                               
7. Threshold(s) that is/are crossed or                                  
reached: 12.5%                                                                        
                                                                               
8: Notified Details: 2,000,000                                                  
                                                                               
A: Voting rights attached to shares                                            
                                                                               
Class/type   Situation         Resulting situation after the triggering        
of shares    previous to the   transaction                                     
             triggering                                                        
If possible  transaction                                                       
use ISIN                                                                       
code                                                                           
                                                                               
                                                                               

             Number of    Number Number    Number of voting     Percentage of   
             shares       of     of        rights               voting rights   
                          voting shares                                      
                          rights                                             
                                           Direct      Indirect Direct Indirect 
                                                                
Ordinary     Below        Below  2,000,000 2,000,000            12.5%          
Shares       3%           3%                                          
                                                                
GB00B02TDY97                                                    

B: Financial Instruments                                                       
                                                                               
Resulting situation after the triggering transaction                           
                                                                               
Type of        Expiration     Exercise/       No. of voting      Percentage of 
financial      date           conversion      rights that may be voting rights 
instrument                    period/date     acquired (if the                 
                                              instrument                       
                                              exercised/                       
                                              converted)                       
                                                                               

Total (A+B)                                                                    
                                                                               
Number of voting rights                 Percentage of voting rights            
                                                                               
2,000,000                               12.5%                                  

9. Chain of controlled undertakings through which the voting rights and /or the
financial instruments are effectively held, if applicable:                     
                                                                               
Singer Capital Markets Limited controls as principal 2,000,000 shares which are
held through its nominee, New Street Nominees Limited.                         

Proxy Voting:                                                                  
                                                                               
10. Name of proxy holder:                                                      
                                                                               
11. Number of voting rights proxy                                              
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                   

13. Additional information:             Based on issued share capital of 16,041,491                                   
                                                                                                                     
14 Contact name:                        Mareike Stamm                          
                                                                               
15. Contact telephone number:           0203 205 6622                          

For further information please contact:

Creon Corporation Plc Jonathan Freeman +44 (0)20 7752 0215

Daniel Stewart & Company Plc Oliver Rigby +44 (0)207 776 6550

GTH Media Relations Toby Hall +44 (0)20 7153 8039

Christian Pickel +44 (0)20 7153 8036


                 

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