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Creon Corporation plc (AMED)

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Thursday 18 December, 2008

Creon Corporation plc


For immediate release:


                             Creon Corporation Plc                             

                      ("Creon", "Company" or the "Group")                      

                   NOTIFICATION OF MAJOR INTEREST IN SHARES                    

The Directors of Creon Corporation (AIM: CRO) have been notified that Loxdale
Limited ("Loxdale") have acquired 3,250,000 ordinary shares in the capital of
the Company.

Loxdale's holding in the Company represents approximately 11.6% of the issued
ordinary share capital of the Company.

                                   - Ends -                                    

For further information please contact:

Creon Corporation Plc Jonathan Freeman +44 (0)20 7752 0215

Daniel Stewart & Company Plc Oliver Rigby +44 (0)207 776 6550

GTH Media Relations Toby Hall +44 (0)20 7153 8039

Christian Pickel +44 (0)20 7153 8036


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