Holding(s) in Company

Oxford Instruments plc has been notified that:-

Schroders plc now holds Indirect voting rights of 5,745,884 which represents
11.64% of the issued share capital of the Company.

The Registered Holders of these voting rights are as follows:

Schroder Investment Management Limited 5,256,799

Schroder Investment Management North
America Limited                          487,085

Schroder & Co Limited                      2,000

23 April 2008

Jo Young

Company Secretarial Assistant

Oxford Instruments plc

TEL: [phone]