Holding(s) in Company

Oxford Instruments plc has been notified today that BT Pension Scheme Trustees
Limited as trustee of the BT Pension Scheme and Hermes Pension Management
Limited has an interest in 6,336,062 (Indirect) Ordinary Shares of 5p each
which, represents 12.844% of the issued share capital of the Company. The
number of Indirect voting rights is also 6,336,062.

Of the above amount Hermes UK Small Companies Focus Fund has a direct interest
in 5,374,673 Ordinary Share of 5p each which represents 10.895% of the issued
share capital of Oxford Instruments plc.

BT Pension Scheme Trustees Limited is the parent undertaking of Britel Fund
Trustees Limited, which is the parent undertaking of Hermes Pension Management
Limited. Hermes Pensions Management Limited is the parent undertaking of:

 1. Hermes Investment Management Limited (voting rights held in this issuer
    0.067%)
   
 2. Hermes Focus Asset Management Limited (voting rights held in this issuer
    12.466%)
   
 3. Hermes Assured Limited (included with No 1 above)
   
 4. Hermes Equity Ownership Services Limited (voting rights held in this issuer
    0.311%)
   
Susan Johnson-Brett

Company Secretary

Oxford Instruments plc

21 November 2007