Holding(s) in Company

The Company has been notified today that GAM London Limited has a notifiable
interest in 2,910,227 ordinary shares of 5p each, which represents 5.985% of
the issued share capital of Oxford Instruments plc.

The shares to which this notification relates are registered as follows:

Fund Name                                    Nominal      % of issue   
                                                                       
GAM UK Diversified                           1,477,000    3.037        
                                                                       
GAM Exempt Trust - UK Opportunities            639,000    1.314        
                                                                       
SJP GAM Managed - Life                         485,000    0.997        
                                                                       
SJP GAM Managed - Pension                      309,227    0.636        
                                                                       
                                       TOTAL 2,910,227    5.985