Holding(s) in Company

5 September 2006

1. Royal Mail Pension Trustees Limited

Oxford Instruments plc has been notified pursuant to Section 198-220 of the
Companies Act 1985 that Royal Mail Pension Trustee Limited has a material
interest in 5,414,726 ordinary shares of the Company, representing 11.109% of
the issued share capital as follows:

No of Shares Held  Nominee/Registered Name        Holding                      
                                                                               
5,414,726          11.109%                        Indirect Holding             

2. Britel Fund Trustees Limited for Trustees of BT Pension Scheme

Oxford Instruments plc has been notified pursuant to Section 198-220 of the
Companies Act 1985 that Britel Fund Trustees Limited - The Trustees of BT
Pension Scheme has a material interest in 5,969,027 ordinary shares of the
Company, representing 12.246% of the issued share capital as follows:

No of Shares Held  Nominee/Registered Name        Holding                      
                                                                               
87,944             Britel Fund Nominees Ltd       Direct Holding               
                                                                               
404,357            Chase Nominees Ltd - Hermes    Subsidiary Holding           
                   Assured Limited                                             
                                                                               
5,476,726          Chase Nominees Ltd - Hermes UK Indirect Holding             
                   Small Companies Focus Fund                                  
                   (SU)                                                        

3. Essex County Council

Oxford Instruments plc has been notified for the purposes of Section 198 of the
Companies Act 1985 that the Essex County Council Pension Fund is a limited
partner in the Hermes UK Small Companies Focus Fund. As a limited partner the
Essex County Council Pension Fund has an interest in these shares:

No of Shares Held  Percentage of Shares Held      Nominee/Registered Name      
                                                                               
4,076,726          8.364%                         Chase Nominees Limited