Holding(s) in Company

Oxford Instruments plc has been notified today, pursuant to Section 198 of the
Companies Act 1985 (for the purposes of Section 208 and 209 of the Act), that
HBOS plc and its subsidiaries have a material interest of 1,812,232 Ordinary £
0.05p shares in our Company, which represents 3.781% of the shares in issue.

The shares to which this notification relates are registered as follows:

No of Shares       Fund                      Registered Holder               
                                                                             
5             N/A             HSDL Nominees Limited                          
                                                                             
88,000        SJPI RF59       HSBC Global Custody Nominees (UK) Ltd a/c      
                              823861                                         
                                                                             
403,227       SJP RF42        HSBC Global Custody Nominees (UK) Ltd a/c      
                              872860                                         
                                                                             
660,000       SJPI RF62       HSBC Global Custody Nominees (UK) Ltd a/c      
                              823770                                         
                                                                             
661,000       SJP RF32        HSBC Global Custody Nominees (UK) Ltd a/c      
                              872859