Final Results and Investor Presentation

Summary by AI BETAClose X

Probiotix Health PLC reported a significant increase in sales for the year ended December 31, 2025, reaching £2.73 million, a 45% rise from £1.88 million in 2024, with gross profit also growing by 46% to £1.48 million. The company successfully reduced its EBITDA loss from continuing operations by 34% to £426,000, while improving its gross profit margin to 54%. Probiotix Health ended the year with a cash balance of £1.27 million and remains fully funded, having launched ten new products during the period. The company noted a positive start to 2026, achieving profitability in the first quarter with a record order book of £1.3 million, up 110%.

Disclaimer*

Probiotix Health PLC
30 March 2026
 

30 March 2026

           

ProBiotix Health plc

("ProBiotix" or the "Company" or, together with its subsidiary, the "Group")

 

Final Results and Investor Presentation

 

ProBiotix Health plc (AQSE: PBX), the life sciences business developing probiotics to support cardiometabolic health, announces its audited results for the year ended 31 December 2025.

 

Key Highlights

 

·    Sales +45% to £2.73m (2024: £1.88m)

·    Gross Profit +46% to £1.48m (2024: £997,000)

·    EBITDA loss from continuing operations down 34% to £426,000* (2024: £642,000*)

·    Gross Profit margin improved to 54% (2024: 53%)

·    Group remains fully funded with a cash balance of £1.27m

·    10 new products launched during the year

 

*Before share based payment expenses

 

Post period-end

 

·    During Q1 2026 the Group has achieved profitability

·    Outlook positive with a record Q1 2026 order book +110% at £1.3m

·    Strong momentum in China, with increasing sales channels being delivered by partner Kemin China Technology

·    Recent launch of new women's health products is gaining further tangible traction - well placed to target an accessible B2B market worth more than $5 billion

·    Planned (and funded) expansion in new metabolic health areas to include prediabetes studies

·    Further margin improvement has been achieved, driven by CMO optimisation

 

Investor Presentation

 

The Company is hosting a presentation for investors via the Investor Meet Company platform today at 10:00 am BST. The presentation is open to all existing and potential shareholders. Questions can be submitted pre-event via your Investor Meet Company dashboard, up until 9:00 am BST today, or at any time during the live presentation.

 

To sign up to the presentation via Investor Meet Company please register using the following link: https://www.investormeetcompany.com/probiotix-health-plc/register-investor

 

 

 

Steen Andersen, CEO of ProBiotix Health, commented: "The current year has started positively, with a record Q1 order book of £1.3 million, reflecting a broader customer base, new contract wins and increased reorder activity.

The Group intends to prioritise further expansion across the Asia-Pacific region, with the Kemin partnership in China expected to contribute increasingly to revenue growth, while also providing geographical diversification.

In Europe, potential regulatory developments relating to cholesterol-lowering ingredients are creating a number of opportunities for LPLDL®. and in the United States, we expect a number of late-stage projects to convert into commercial agreements.

The achievement of Q1 profitability is a significant step change for the business and is testimony to the hard work of the team. With a highly scalable business, record new enquiries, and a significant addressable market, we view the future with considerable confidence."

 

 

For further information, please contact:

 

ProBiotix Health plc

https://probiotixhealth-ir.com/

 

investors@probiotixhealth.com

Steen Andersen, Chief Executive Officer

Miles Nolan, Investor Relations

 



AlbR Capital Limited

Aquis Corporate Adviser and Broker

Tel: 020 7469 0930

 

David Coffman

Dan Harris


 

This announcement contains information which, prior to its disclosure, was considered inside information for the purposes of the UK Market Abuse Regulation and the Directors of the Company are responsible for the release of this announcement.

 

Notes to Editors:

 

ProBiotix is a life sciences company that develops probiotic formulations to support cardiometabolic health. Since its formation, ProBiotix has become recognised as a global leader in microbiome modulating probiotics for use in food supplements and nutraceuticals.

 

The Company has a unique approach: discovering ground breaking probiotics, ensuring their benefits through robust science, and bringing to market effective finished probiotic-based products for human health across the globe.

 

Chairman and Chief Executive's Statement

FY 2025 represented a further year of progress in strengthening the Group's position as a global innovator and commercial partner in probiotic-based cardiometabolic health supplements. The Company continued to execute against its stated strategy, delivering strong revenue growth while advancing operational scalability, and progressing towards profitability.

Revenue growth was achieved through a combination of geographic expansion, new customer acquisition and continued growth from existing customer relationships. During the year, the Group further expanded its presence in the United States and successfully entered the Chinese market, while continuing to invest selectively in infrastructure to support future scale.

The volume of new commercial projects initiated during early FY 2025 provided additional confidence in the relevance of the Group's proprietary technology and its alignment with long-term consumer trends in cardiometabolic health and healthy aging.

Based on the Group's performance and outlook, the Board and Management continue to believe that the Company's underlying fundamentals are not yet fully reflected in its current market capitalisation. Comparisons with peer companies in the probiotics and health supplements sector indicate potential for a re-rating as the business continues to scale.

Results

The Group delivered meaningful progress towards profitability in FY 2025. Revenue increased by 45% to £2.73 million (2024: £1.88 million), reflecting continued commercial traction across core markets. Gross profit increased by 49% to £1.48 million (2024: £0.99 million), with gross margin improving to 54% (2024: 53%).

Other administrative costs increased modestly by 9% to £1.9 million, in line with management expectations and reflecting controlled investment in growth, together with inflationary pressures.

EBITDA loss from continuing operations, before share-based payment charges, reduced by 34% to £426,000 (2024: £642,000), demonstrating the operating leverage within the business model. The company has recognised a share based payments charge in the year of £753,000.

Having achieved the first milestone of £2.5m revenue in a 12 month period, the company are confident the remaining milestones will be achieved so the charge can be recognised over the period in which the targets will be achieved. The charge, which is not a cash cost to the company, is heavily weighted in the first year, the charge for the future years will be significantly reduced. The net loss for the year, including amortisation and share-based payment charges, was £1.2m (2024: £0.8m).

The Group ended the year with cash balances of £1.27 million (2024: £1.65 million), providing adequate resources to support our planned commercial and operational initiatives.

 

Strategic focus and Market Opportunity

 

ProBiotix is a life sciences company with a strategic focus on probiotics and the human microbiome addressing various aspects of cardiometabolic health, and other lifestyle conditions impacting the quality of life throughout the lifespan. The Company operates in the dietary supplement prevention segment, tapping into the mega consumer trend of healthy ageing, cardiometabolic health and probiotics. Our purpose is to provide consumers and industry worldwide with uncompromised supply and service of safe and scientifically validated probioticbased microbiome product solutions for the improvement of human health. The Company aims to partner with scientifically driven dietary supplement suppliers, consumer health and Over The Counter (OTC) companies globally who have a defined strategic focus on the human microbiome.

Our commercial focus is to provide private label, turnkey probiotic dietary supplements to target preventative cardiometabolic health and healthy ageing, taking offset in the Company's principal proprietary and patent protected probiotic strain LPLDL®. In selected markets we complement the value proposition further by including ingredient sales of LPLDL® as a means of accelerating short-term market penetration and building brand awareness.

Cardiovascular disease (CVD) remains the leading cause of deaths globally, ahead of cancer. The latest statistics from the World Heart Federation show that, CVD accounts for approximately 20.5 million deaths annually, representing around 33% of all deaths (Source:
World Heart Federation | Global Heart Health & CVD Advocacy). There are an increasing number of women suffering from CVD, with up to 77% presenting elevated cholesterol levels and up to 5 times higher risk of heart attack during and after menopause (Source: Health Survey for England, 2021 part 2 - Adults' health: Cholesterol). CVD has been identified as one of the key leading causes mortality in middle aged women (Sources: World Heart Federation |Global Heart Health & CVD Advocacy and American Heart Association; Circulation; Women's Health Initiative).

 

Some 30% of all deaths in women are caused by CVD with the global number having risen by nearly 50% to almost 9 million deaths annually over the past 20 years (World Heart Federation | Global Heart Health & CVD Advocacy + Medicine. 104(27):e43215, July 04, 2025). According to the latest research from the World Heart Federation and American Heart Association ( Source: World Heart Federation | Global Heart Health & CVD Advocacy) between 3.6 to 4.4 million people worldwide succumb to high cholesterol annually, and approximately 39% of the global adult population are categorised as having elevated cholesterol, and thereby in the risk group of CVD. With 80% of all CVD deaths being preventable according to WHO and average life expectancy having increased by 6.2 years over the past 30 years (Institute for Health Metrics and Evaluation 2023) the category offers a unique positioning opportunity for ProBiotix Health's product portfolio and technology in a fast expanding market for preventive supplements.

This underlying disease burden is increasingly translating into measurable consumer demand for preventive, science-backed health solutions. According to Innova 73% of global consumers consider healthy ageing "extremely" or "very important" in their day-to-day choices, reflecting a shift towards long-term health maintenance. (Source: Innova Insights)

In the UK, 45%  of consumers agree that adhering to a health plan can help prevent future conditions (Source: Innova Market Insights) Source: Mckinsey & Company) Source: Euro Monitor) of global consumers identify naturalness as their most important eating practice, underscoring growing demand for clinically validated, naturally derived solutions.

The global probiotics supplement consumer market is, in its own right, forecast to reach $12.7 billion by 2028 (https://ipa-biotics.org/human-market.). Market growth is increasingly driven by consumer demand for high quality and clinically backed "precision probiotics" in the area of Cardiometabolic Health, Women's Health and Healthy Ageing. The reduction of cardiometabolic disease-related risk factors remain one of the top priorities for legislators, and thus offers distinct growth opportunities for the category.

 

In addition, the global consumer market for preventive cardiometabolic health supplements is estimated to reach over $16 billion towards 2028 (Source: Precedence Research)

 

A graph of a graph showing the number of people in the market AI-generated content may be incorrect.

A black and blue rectangle with white text AI-generated content may be incorrect.

 

The top five market growth factors for cardiometabolic health supplements can be outlined as follows (source: Precedence Research):

 

📊 Rising Prevalence of Cardiovascular Disease (CVD)

👴 Aging Population

🛡️ Preventive Healthcare Focus

🌍 Growing Disposable Income in Emerging Markets

👩 Increased Consumer Awareness & Health Consciousness

 

As a means of targeting this lucrative market, leading brands are looking to add new products to their lineup based on novel innovative ingredients, and product solutions allowing for clear positioning and differentiation. As a provider of private label turnkey supplements, ProBiotix participates in approximately 20-25% of the value creation in the current $25 billion consumer market, representing a $5-$7.5 billion market potential. With a projected accumulated consumer market value of $30 billion by 2028, the cardiometabolic health and probiotic supplement markets continue to represent a significant opportunity for ProBiotix in a space with a limited number of scientific backed product solutions.

 

 

Key Milestone Achievements in FY 2025

 

 

·    FY2025 delivered a satisfactory result against our stated strategy and operational objectives.

 

·    The strong trading performance reflected robust commercial traction across our core markets, supported by both new customer acquisition, and continued positive growth from already established customer partnerships.

·    We implemented a number of internal initiatives to enhance operational scalability, and enhance the path to profitability.

·    Our recently established partnership with global ingredients specialist Kemin performed strongly during the year, benefiting from the execution of Kemin's highly effective market positioning strategy. The material outcome was realised at the end of the year, less than 12 months after market introduction, with their promising sales pipeline converting to commercial sales.

 

·    The relationship with key customers remained robust, delivering continued growth while at the same time, we managed to further reduce the Company's dependency on a few key customers by the addition of potential cornerstone partners such as Wellizen (Australia), RevivaBio (Sweden) and NutriWow (China).


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·    Material progress towards profitability was reached during the year. EBITDA losses were reduced by 34% to £426,000 in 2025 (2024: £642,000), fully in line with our stated strategic objectives. The gross profit margin edged higher to 54% (2024: 53%), with multiple initiatives underway to further enhance margins in 2026 and beyond, including the conclusion of our regional Contract Manufacturing Organisation (CMO) strategy to improve supply security, closeness to market and cost optimisation.

·    A new menopause-focused women's health concept, based on our LPLDL® strain - YourBiotixMH was launched. Early commercial traction has been positive, with 27 projects currently open, a number of which are in detailed discussion, and the first two product launches are anticipated for early 2026. The interest in these new products is driven by growing consumer focus on science-backed solutions in women's health and healthy ageing.

 

·    Commercial traction continued to build throughout the year. In 2025 we generated a significant increase in enquiries, with over 280 'qualified leads' (2024: 190). This has been driven by our participation in major global industry events, including SupplySide Global (USA), Vitafoods Europe (Spain) and Vitafoods Asia (Thailand). The active customer portfolio expanded by approximately 50%, following the successful onboarding of new customers across multiple geographies.

·    We also continued to strengthen our scientific and clinical foundations. Applications were submitted for ethical committee approval for two new clinical trials. The first, a three-year study expected to include over 200 participants, will investigate the potential benefits of LPLDL® in individuals with pre-diabetes, type I diabetes and type II diabetes. A successful outcome could support future expansion of LPLDL® into the preventive pre-diabetes category. The second trial, with approximately 60 participants, is designed to further reinforce the clinical evidence supporting the role of LPLDL® cardiometabolic health and cholesterol reduction. 

·    Geographic expansion progressed well during the year, with entry into the Korean market through the launch of our CholBiome X3, a finished product containing the Company's proprietary LPLDL® ingredient. The launch was executed in partnership with P.Bros, Korea's leading influencer-driven online pharmacy platform.

·    The current five-year strategy plan was successfully updated and replaced with a new three-year strategy looking towards 2028.


Board and Management

There were no changes to the composition of the Board or senior management during FY 2025. The Board considers the current structure to be appropriate to support the Group's near and medium-term objectives. Incremental additions may be made as the business continues to scale.

 

Outlook

FY 2026 commenced positively, with a record Q1 order book of £1.3 million, reflecting a broader customer base, new contract wins and increased reorder activity.

The Group intends to prioritise further expansion across the Asia-Pacific region, with the Kemin partnership in China expected to contribute increasingly to revenue growth, while also providing geographic diversification.

In Europe, potential regulatory developments relating to cholesterol-lowering ingredients are creating a number of opportunities for LPLDL®, The Company is engaged in several active replacement projects, with an initial major product launch expected in H1 2026.

In the United States, management expects a number of late-stage projects to convert into commercial agreements. While short-term macroeconomic and trade-related uncertainties may impact the pace of expansion, no material long-term impact is anticipated, supported by ongoing localisation of manufacturing.

The Group remains adequately funded to execute its growth strategy. Admission to the Apex Segment of the Aquis Stock Exchange during the year marked an important milestone, reflecting the Company's scale and governance maturity, and supporting continued engagement with institutional and private investors.

With a highly scalable business, record new enquiries, and a significant market to address, we view the future with considerable confidence.

 

A Reynolds

S Andersen

Chairman

Chief Executive Officer

 

Date: 27 March 2026

 

REVIEW OF BUSINESS

 

A review of the business of the Group, together with comments on future developments is given in the Chairman's and Chief Executive's Statements.

 

PRINCIPAL RISKS AND UNCERTAINTIES FACING THE GROUP

Technology and products

 

The Group is involved in the discovery and development of microbiome modulation products. The development and commercialisation of its intellectual property and future products will require human nutritional studies and there is a risk that products may not perform as expected. This risk is common to all new products developed for human consumption.

 

Technologies used within the food, beverage and healthcare marketplace are constantly evolving and improving.

 

There is a risk that the Group's products may become outdated or their commercial
value decrease as improvements in technology are made and competitors launch competing products. To mitigate this risk the Group is working with industry key opinion leaders, attends international conferences and has developed a research and development department which will keep up with the latest developments in the industry.

 

Intellectual Property

 

The Group is focused on protecting its IP and seeking to avoid infringing on third parties' IP. To protect its products, the Group is building and securing patents to protect its key products. However, there remains the risk that the Group may face opposition from third parties to patents that it seeks to have granted and that the outstanding patent applications are not granted. The Group engages legal advisers to mitigate the risk of patent infringement and to assist with the protection of the Group's IP.

KEY PERFORMANCE INDICATORS

 

Financial

 

 

 

 

Year to 31 December   2025

 

Year to 31 December   2024

 

 

£'000

£'000

 

 

 


Revenue


2,732

1,883

Operating Loss


(1,235)

(852)

Loss for the period


(1,233)

(847)

Cash as at 31 December 2025


1,266

1,646

 



 

 

During the year to 31 December 2025 the company has achieved a number of key objectives to build shareholder value, these are laid out in the Chairman and Chief Executive's statement.

 

Non-financial

 

The Board recognises the importance of KPI's in driving appropriate behaviour and enabling of Group performance. For the year to 31 December 2025 the primary KPI's were to develop customer relationships established in 2024 to successful contract relationships and onboarding in FY 2025. In 2025 the customer portfolio expanded to 23 customers from 13 in 2024.

 

DIVIDENDS

No dividends are distributed for the year to 31 December 2025. (2024: NIL)

 

FUTURE DEVELOPMENTS

The Chairman's and Chief Executive statement on gives information on the outlook of the Group.

 

Corporate Governance

 

Executive Management:

 

The Group's current executive team comprises:

 

A Reynolds          

Non-Executive Chairman

S Andersen

Executive Director and CEO

S O'Hara

Non-Executive Director

M Caspani

Non-Executive Director

F Bruhn-Petersen

Non-Executive Director

           

Corporate Responsibility

 

The Board takes regular account of the significance of social, environmental and ethical matters affecting the Group wherever it operates.  It has developed a specific set of policies on corporate social responsibility, which seek to protect the interests of all of its stakeholders through ethical and transparent actions and include an anti-corruption policy and code of conduct. 

 

Corporate Governance:

 

The Group is committed to high standards of corporate governance and seeks to continually evaluate its policies, procedures and structures to ensure that they are fit for purpose. In order to protect the interests of its shareholders and other stakeholders the Board has chosen to adopt the Quoted Companies Alliance (QCA) Corporate Governance Code for Small and mid-size Quoted Companies (the "QCA Code"), and the Directors are always

prepared, where practicable, to enter into dialogue with all such parties to promote a mutual understanding of objectives.

 

Full details of the Company's policy on Corporate Governance can be found on the website under:

 

https://probiotixhealth-ir.com/corporate/corporate-governance

 

Composition of the Board of Directors

 

The Board of Directors is currently comprised of the Chairman, Chief Executive Officer, Commercial Director, Executive Director and the three Non-Executive Directors. 

 

Role of the Board:

 

The role of the Board is to agree the Group's long-term strategy and direction and to monitor achievement of its business objectives. The Board meets several times per annum, either virtually or in person. Furthermore, it holds additional meetings as are necessary to transact ongoing business.

 

Board Committees:

 

Remuneration Committee

 

The Remuneration Committee is made up of Adam Reynolds, as Chairman with Marco Caspani has access to external expertise should that be required. This committee is responsible for the scale and structure of the remuneration of the Chief Executive, the Executive Directors and reports to the Chief Executive. The recommendations of the committee must be approved by the Board of Directors.  No director or manager shall be involved in decisions relating to his/her own remuneration.

 

AQSE Rules Compliance Committee

 

The AQSE Rules Compliance Committee is chaired by Adam Reynolds. This committee is charged with ensuring that the Group has sufficient procedures, resources and controls in place to ensure compliance with the AQSE rules for companies. Among other things, the committee shall ensure that an Executive Director is at all times able to respond to requests for information from the Corporate Adviser and that all Directors and employees are aware of their obligations with regards to the disclosure of any trading in the Group's shares.

 

Audit Committee

 

The Audit Committee, is chaired by Marco Caspani with Adam Reynolds. This committee is required to monitor the integrity of the financial statements of the Group, including the interim and annual reports.  The committee also reviews financial returns to regulators and any financial information contained in announcements of a price sensitive nature.  The committee shall also consider and make recommendations to the Board regarding resolutions to be put to shareholders for approval at the Annual General Meeting, with respect to the appointment or re-appointment of the Group's external auditors. The Audit Committee, together with the external auditors, are responsible for determining the scope of the annual audit.

 

Nomination Committee

 

The Company does not currently have a nomination committee as the Board does not consider it appropriate to establish such a committee at this stage of the Company's development. Decisions which would usually be taken by the nomination committee will be taken by the Board as a whole.

 

Employees

 

The Group engages its employees in all aspects of the business and seeks to remunerate them fairly.  The Group gives full and fair consideration to applications for employment regardless of age, gender, colour, ethnicity, disability, nationality, religious beliefs or sexual orientation.  The Board takes employees' interest into account when making decisions. Any suggestions from employees aimed at improving the Group's performance are welcomed.

Suppliers and Contractors

 

The Group recognises that the goodwill of its contractors, consultants and suppliers is crucial to the success of its business and seeks to build and maintain this goodwill through fair and transparent business practices. The Group aims to settle genuine liabilities in accordance with contractual obligations.

 

Health and Safety

 

The Board recognises that it has a responsibility to provide strategic leadership and direction in the development and maintenance of the Group's health and safety strategy, in order to protect all of its stakeholders

 

Section 172 Statement

In accordance with s172 of the Companies Act 2006 the Directors recognise their duty to promote the success of the company for the benefit of its stakeholders. Our commitment to delivering scientifically validated, safe, and effective probiotic-based microbiome solutions is underpinned by robust governance and a stakeholder-focused approach.

 

Stakeholder Engagement

Our stakeholders include customers, employees, suppliers, investors, regulators, and the wider community. During the year, the Board actively engaged with each group through various initiatives:

·      Customers - We continue to invest in scientific research and product innovation to uphold our promise of uncompromised safety and efficacy in microbiome health solutions. Market trends, customer feedback mechanisms and collaborations with leading institutions guide our development.

·      Employees - The wellbeing and development of our employees remain central to our strategy. Initiatives such as involvement in strategic development, a flat management structure, freedom to plan securing a healthy work/life balance,  training programs and employee engagement forums foster a positive workplace culture.

·      Suppliers - Ethical sourcing and sustainability remain priorities. We work closely with supplier partnerships to ensure high-quality ingredients and sustainable supply chains, fostering long-term partnerships.

·      Investors - Transparent communication and long-term value creation define our investor relations approach. Regular reporting and investor engagements demonstrate our strategic vision.

·      Regulators - We adhere to the highest regulatory and compliance standards, ensuring product safety and scientific integrity. Strategic membership of industry leading organisations like the International Probiotic Association (IPA) ensures we remain aligned with current and future product regulation and legislation. Active engagement with regulatory bodies including AQUIS enables alignment with evolving industry standards and listing rules.

Long-Term Value and Sustainability

Recognising the importance of sustainability, we continue to integrate environmental and social responsibility into our business. Initiatives such as, responsible packaging, and ethical research practices support our long-term commitment to the health of people and the planet.

Board Decision-Making and Governance

The Board considers the interests of stakeholders in its decision-making processes. This includes evaluating risks, strategic opportunities, and industry developments to ensure resilient growth while maintaining ethical leadership.

We remain committed to upholding the principles of Section 172, ensuring that our actions contribute positively to society, safeguard stakeholder interests, and support sustainable long-term business success.

 

ON BEHALF OF THE BOARD

 

S Andersen

Date 27 March 2026

 

The Directors present their report and the audited financial statements of the group for the year to 31 December 2025.

 

PRINCIPAL ACTIVITY

The principal activity is that of developing probiotics to tackle cardiovascular metabolic health disease and other lifestyle conditions which are affecting growing numbers of people across the world.

 

DIRECTORS

The directors who served the company during the year and up to the date of this report were as follows:

 

Executive Directors

S Andersen

 

Non-executive Directors

M Caspani

A Reynolds

F Bruhn-Petersen

S P O'Hara

 

Directors' Remuneration

 

Details of emoluments received by Directors of the Group for the year ended 31 December 2025 are as follows:


Remuneration

 

Share based

Pension Costs

Total


and fees

Bonuses

Payments

 

 


£'000

£'000

£'000

£'000

£'000

A Reynolds*

60,000

-

77,200

-

137,200

S Andersen*

264,218

-

198,246

12,938

475,402

S P O'Hara*

21,000

-

231,600

-

252,600

M Caspani*

21,000

-

7,000

-

28,000

F Bruhn-Petersen*

21,000

-

-

-

21,000

Total

387,218

-

514,046

12,938

914,202

 

 

Share based payments is an accounting charge and not remuneration paid to directors.

 

Directors and their interests

 

The directors of the group held the following beneficial interests in the shares and share options of Probiotix at the date of this report:

 


Issued Share Capital

Share Options


Ordinary


Ordinary

Option


shares of

Percentage

shares of

exercise


£0.0005 each

Held

£0.0005 each

Price (£)






S P O'Hara

6,131,450

3.88

3,000,000

0.210

M Caspani

-

-

500,000

0.210

A Reynolds

442,857

0.28

1,000,000

0.210

S Andersen

125,450

0.04

5,000,000

0.095

F Bruhn-Petersen

3,000,000

1.90

-

-






 

The share options held by S P O'Hara, and A Reynolds were granted on 31 March 2022 and are exercisable at £0.21 at any time up 30 March 2032, 50% of which vest on a doubling of the share price to £0.42 and 50% on an annual turnover of £2.5m

 

The share options held by M Caspani were granted on 31 March 2022 and are exercisable at £0.21 at any time up 30 March 2032, 1/3 of which vest on each of the 2-4 anniversaries of the date of grant.

 

The share options held by S Andersen were granted on 10 February 2025 and are exercisable at £0.095 at any time up 18 February 2035 50% vest when annual turnover reaches £2.5m, 50% vest on annual turnover of £5m.

 

Directors and Officers Insurance

 

The Group have a directors and Officers Insurance policy for £1m managed by CFC Underwriting Limited

 
SUBSTANTIAL SHAREHOLDINGS

Substantial shareholdings include directors as at 27 March 2026 were as follows:          

                       


% of shares issued

Optibiotix Health plc

33.85

Holdingselskabet of 29. Juni 2010 Aps.

20.97

Seneca Partners

5.07

Stephen O'Hara

3.88

 

The share price per share at 31/12/2025 was £0.0775 (31/12/2024: £0.0625).

 

FINANCIAL INSTRUMENTS

The Group's exposure to financial risk is set out in note 21 to the financial statements.

 

FINANCIAL AND CAPITAL RISK MANAGEMENT

The directors constantly monitor the financial risks and uncertainties facing the Group with particular reference to the exposure of credit risk and liquidity risk. They are confident that suitable policies are in place and that all material financial risks have been considered. The financial risk management objectives and policies can be found within note 21 of the financial statements.

 

The Board's objective is to maintain a balance sheet that is both efficient and delivers long term shareholder value.  The Group had cash balances of £1.27m at 31 December 2025 (2024: £1.65m) and had no short-term borrowings. The Board continues to monitor the balance sheet to ensure it has an adequate capital structure.

 

 

PRINCIPAL RISKS AND UNCERTAINTIES

 

Market Risks

Impact

Mitigation

 

 

Economic

uncertainty caused by changes in US policy

 

 

Ongoing uncertainty in trade relations following the change in the US administration

 

 

Manufacturing of some products has changed with effect from January 2026 to mitigate any major impacts on the business of the tariff regime. There was a small charge for tariff expenditure in 2025 £14k generally the business has been unaffected.

Economic uncertainty caused by war in Ukaine

Ongoing economic uncertainty, recession or an escalation of the war in Ukraine may impact market confidence, demand and prices.

The group is not directly affected by the war in Ukraine, but the Board monitor the general economic environment and consider economic forecasts when taking key decisions. The impact of the war in the middle east is under consideration and management will take appropriate action

Technology

The Group's platform is currently unique. Rapid technological advances could see competitor products being launched.

The Group has product development plans in place for improved technology as well as for a wider product portfolio that includes additional innovative solutions for the targeted consumer groups.

 

Financial Risks

Impact

Mitigation

Future funding requirements

 Potential as yet unidentified opportunities may not be pursued with the existing funding.

Management will analyse major opportunities and present them in additional business cases when warranted. The Company is able to sell its listed investments and raise further equity and debt finance.

 

 

 

Legal Risks

Impact

Mitigation

Intellectual Property litigation

Any claim brought against us would detract the Company from its business and incur potentially significant costs in defending its IP.

The Group engages with IP specialists to ensure we have a strong position. To our knowledge we do not infringe on any patents.

Compliance risks

The Group operates in many jurisdictions across the world. Local compliance issues may have an impact on the company.

Company maintains strong relationships with clients and monitors changes in local compliance laws which may have an impact.

 

 

 

PRINCIPAL RISKS AND UNCERTAINTIES (Continued)

 

Operational Risks

Impact

Mitigation

Loss of key personnel

Material adverse impact on the Group's

financial condition and prospects.

Competitive remuneration and option packages to reduce market volatility. The remuneration committee oversees the level of remuneration to ensure it remains competitive.

Technology

The Group is commercialising its technology to launch new products  in the consumer market.

The Group has identified a need and responded to consumer demand.

Commercialisation

The Group has relied on sales to one customer in the early stages of commercialisation. A change in that customer outlook would affect Group sales growth.

The Group recruited experienced  sales management team who have delivered a broad range of new customers to mitigate the reliance on one customer.




Cyber attacks

Cyber-attacks could delay or impair operations as which would have financial implications.

Training, anti-virus software, all users have multifactor authorisation for accounts, weekly review of attempts

 

 

 

RESEARCH AND DEVELOPMENT

The Chairman and Chief Executive's Statement gives information on the Group's research and development activities.

 

EVENTS AFTER THE REPORTING PERIOD

There are no events after the reporting date.

 

PUBLICATION OF ACCOUNTS ON GROUP WEBSITE

Financial statements are published on the Group's website. The maintenance and integrity of the website is the responsibility of the Directors. The Directors' responsibilities also extend to the financial statements contained therein.

 

GOING CONCERN

The financial statements have been prepared on the assumption that the Group is a going concern. When assessing the foreseeable future, the Directors have looked at the Cash forecast for the next 12 months from the date of this report, the cash at bank available as at the date of approval of this report and are satisfied that the Group should be able to cover its committed  cost, and  other administrative expenses, as well as its ongoing research and development expenditure

 

After assessing the current loss making position, plausible downside scenarios, and based on strong revenue and forecasts, the directors have a reasonable expectation that the Group and the Company have adequate resources to continue in operational existence for the foreseeable future. Accordingly, they continue to adopt a going concern basis in preparing the annual report and financial statements.

 

STATEMENT OF DIRECTORS' RESPONSIBILITIES

The Directors are responsible for preparing the annual report and the financial statements in accordance with applicable law and regulations. Company law requires the directors to prepare financial statements for each financial period. Under that law the directors have elected to prepare financial statements in accordance with UK adopted international accounting standards.

Under Company law the Directors must not approve the financial statements unless they are satisfied that they give a true and fair view of the state of affairs of the Group and Parent Company as at the end of the financial year and of the profit and loss of the Group for that period. In preparing these financial statements, the Directors are required to:

·    select suitable accounting policies and then apply them consistently;

·    make judgements and accounting estimates that are reasonable and prudent;

·    state whether the Group and Parent Company financial statements have been prepared in accordance with UK adopted international accounting standards subject to any material departures disclosed and explained in the financial statements;

·    prepare the financial statements on a going concern basis unless it is inappropriate to presume that the Group and Parent Company will continue in business.

The Directors confirm that they have complied with the above requirements in preparing the financial statements.

The Directors are responsible for keeping adequate accounting records that are sufficient to show and explain the Group's and Parent Company's transactions and disclose with reasonable accuracy at any time the financial position of the Group and Parent Company to enable them to ensure that the financial statements comply with the Companies Act 2006. They are also responsible for safeguarding the assets of the Company and Group and hence for taking reasonable steps for the prevention and detection of fraud and other irregularities.

The Directors are responsible for the maintenance and integrity of the corporate and financial information included on the Group's website. Legislation in the United Kingdom governing the preparation and dissemination of financial statements and other information included in Directors' Reports may differ from legislation in other jurisdictions.

 

STATEMENT AS TO DISCLOSURE OF INFORMATION TO AUDITORS

So far as the Directors are aware, there is no relevant audit information (as defined by Section 418 of the Companies Act 2006) of which the Group and Parent Company auditor is unaware, and each Director has taken all the steps that he ought to have taken as a Director in order to make himself aware of any relevant audit information and to establish that the Group and Parent Company auditor is aware of the information.

 

AUDITOR

Gerald Edelman LLP has indicated its willingness to continue in office as auditor of the Company, and a resolution to re-appoint Gerald Edelman LLP will be proposed at the forthcoming Annual General Meeting.

STRATEGIC REPORT

In accordance with section 414C(11) of the Companies Act 2006 the Group chooses to report the future outlook and the risks and uncertainties faced by the Group in the Strategic Report.

 

ON BEHALF OF THE BOARD

 

S Andersen

Date 27 March 2026

Opinion

 

We have audited the financial statements of Probiotix Health PLC (the 'parent company') and its subsidiaries (the 'group') for the year ended 31 December 2025 which comprise the consolidated statement of comprehensive income, consolidated and company statements of financial position, consolidated and company statements of changes in equity, consolidated and company statement of cash flow, and notes to the consolidated and company financial statements, including a summary of significant accounting policies.

 

The financial reporting framework that has been applied in the preparation of the group financial statements is applicable law and UK adopted International Accounting Standards in conformity with the requirements of the Companies Act 2006. The financial reporting framework that has been applied in the preparation of the parent company financial statements is applicable law and United Kingdom Adopted International Accounting Standards.

 

In our opinion:

·      the financial statements give a true and fair view of the state of the group's and of the parent company's affairs as at 31 December 2025 and of the group's loss for the year then ended;

·      the group financial statements have been properly prepared in accordance with UK adopted International Accounting Standards;

·      the parent company financial statements have been properly prepared in accordance with UK adopted International Accounting Standards in conformity with the requirements of the Companies Act 2006; and

·      the financial statements have been prepared in accordance with the requirements of the Companies Act 2006.

Basis for opinion

 

We conducted our audit in accordance with International Standards on Auditing (UK) (ISAs (UK)) and applicable law. Our responsibilities under those standards are further described in the Auditor's responsibilities for the audit of the financial statements section of our report. We are independent of the Group and company in accordance with the ethical requirements that are relevant to our audit of the financial statements in the UK, including the FRC's Ethical Standard as applied to listed entities, and we have fulfilled our other ethical responsibilities in accordance with these requirements. We believe that the audit evidence we have obtained is sufficient and appropriate to provide a basis for our opinion.

 

Independence

 

We remain independent of the Group and the Company in accordance with the ethical requirements that are relevant to our audit of financial statements in the UK, including the FRC's Ethical Standard as applied to listed entities, and we have fulfilled our other ethical responsibilities in accordance with these requirements.

 

Conclusions relating to going concern

 

In auditing the financial statements, we have concluded that the director's use of the going concern basis of accounting in the preparation of the financial statements is appropriate. Our evaluation of the directors' assessment of the Group and parent company's ability to continue to adopt the going concern basis of accounting included reviews of cash reserves and critical review of forecasts for a period of 12 months from when the financial statements are authorised for issue.

 

Based on the work we have performed, we have not identified any material uncertainties relating to events or conditions that, individually or collectively, may cast significant doubt on the group's ability to continue as a going concern for a period of at least twelve months from when the financial statements are authorised for issue.

 

Our responsibilities and the responsibilities of the directors with respect to going concern are described in the relevant sections of this report.

 

 

Overview

Coverage

100% of Group loss before tax

100% of Group total assets

Key audit matters

Revenue recognition has been identified as a key audit matter this year. This is essentially due to material increase in revenue through expansion in new geographies this year, and material revenue balance generated from a small number of high value customers.

 

Impairment review of intangible assets (development cost and patents) and Going concern were key audit matters in the last year, however, in the current year these were not assessed and concluded as a key audit matter. This is based on our audit of impairment indicators review performed by management not resulting in any indicators requiring a full impairment review and our audit of going concern cash forecast prepared by management showing a strong net cash position.  

 

 

Materiality

Group financial statements as a whole £41,000 (£33,000: 2024) based on 1.5% of gross assets. Company financial statements as a whole £20,000 (£14,000: 2024) based on 1.5% of gross assets.

 

 

An overview of the scope of our audit

 

As part of designing our audit, we determined materiality and assessed the risks of material misstatement in the financial statements. In particular, we looked at where the directors made subjective judgments, for example in respect of significant accounting estimates that involved making assumptions and considering future events that are inherently uncertain. As in all of our audits we also addressed the risk of management override of internal controls, including evaluating whether there was evidence of bias by the directors that represented a risk of material misstatement due to fraud.

 

 

 

We tailored the scope of our audit to ensure that we performed enough work to be able to give an opinion on the financial statements as a whole, taking into account the structure of the Group and the Company, the accounting processes and controls, and the industry in which they operate.

The Company and Probiotix Limited are significant components and were subject to full scope audit procedures by the Group audit team. Our audit scope for the non-significant components included performance of analytical review procedures. We also performed specified audit procedures over certain account balances and transaction classes that were regarded as material to the Group with a view to improve overall group audit coverage.

 

Key audit matters

 

Key audit matters are those matters that, in our professional judgement, were of most significance in our audit of the financial statements of the current period and include the most significant assessed risks of material misstatement (whether or not due to fraud) we identified, including those which had the greatest effect on, the overall audit strategy, the

allocation of resources in the audit; and directing the efforts of the engagement team. These matters were addressed in the context of our audit of the financial statements as a whole, and in forming our opinion thereon, and we do not provide a separate opinion on these matters.

 

 

Key audit matter

How our audit addressed the key audit matter

Revenue recognition

The group has recognized £2.7 million of revenue this year which has been identified as a key audit matter. This is essentially due to material increase in revenue through expansion in new geographies this year, and material revenue balance generated from a small number of high value customers.

The primary revenue stream arises from the sale of products to business customers. There is a risk as to whether the revenue recognised meets the revenue recognition criteria under IFRS 15, particularly on the occurrence of the transaction or if an appropriate cut-off is applied in this regard. There is also a risk if the Group's accounting policy is compliant with the requirements of IFRS.

Refer to Accounting Policies, Note 2.1

We have performed the following audit procedures:

 

·    Obtained an understanding of the revenue recognition process through walkthroughs and assessed the design and implementation of key controls involved in revenue recognition particularly with regards occurrence and cut-off.

·    Obtained and reviewed new or amended customer contracts (and any significant side letters) entered into during the year to assess whether revenue has been recognised in accordance with IFRS 15;

·    For a sample of revenue transactions, tested revenue recognised in accordance with IFRS 15 and contractual terms;

·    Performed cut-off testing around the year end by testing a sample of transactions immediately pre- and post-year end to confirm revenue is recognised in the correct accounting period;

·    Tested the completeness and accuracy of revenue by reconciling revenue per the Contracts / POs to the general ledger and investigated reconciling items where appropriate; and

·    Evaluated the adequacy of accounting policy and disclosures in in the financial statements under IFRS 15.

 

Key observations:

Based on the audit work performed, we are satisfied that the revenue is appropriately  recognised for the year ended 31 December 2025.

 

 

Our application of materiality

 

Materiality is assessed as the magnitude of an omission or misstatement that, individually or in the aggregate, could reasonably be expected to influence the economic decisions of the users of the financial statements. Misstatements below these levels will not necessarily be evaluated as immaterial as we also take account of the nature of identified misstatements, and the particular circumstances of their occurrence, when evaluating their effect on the financial statements as a whole. Materiality provides a basis for determining the nature and extent of our audit procedures.

Based on our professional judgment, we determined materiality for the financial statements as a whole as follows:

 

Overall materiality

£41,000 (£33,000: 2024)

£20,000 (£14,000: 2024)

How we determined it  

1.5% of revenue

 

                                        

1.5 % of administrative expenses

Rationale for benchmark applied

We believe that gross assets is a primary measure used by shareholders in assessing the performance of the group.

We believe that gross assets is a primary measure used by shareholders in performance of the Company as the holding company within the Group.

Performance materiality

£26,000 (£21,000: 2024)

£13,000 (£9,000: 2024)

Basis for determining performance materiality

65% of materiality. In reaching our conclusion on the level of performance materiality to be applied we considered a number of factors including the expected total value of known and likely misstatements (based on past experience), our knowledge of the Group's control environment and management's attitude towards proposed adjustments.

65% of materiality. In reaching our conclusion on the level of performance materiality to be applied we considered a number of factors including the expected total value of known and likely misstatements (based on past experience), our knowledge of the Group's control environment and management's attitude towards proposed adjustments.

 

Component materiality

 

 

For each component in the scope of our Group audit, we allocated a materiality that is equal to or less than our overall Group materiality. The range of materiality allocated across components ranged from £16,400 to £36,900. We set materiality for each significant component of the Group based on a percentage of between 40% and 92% of Group materiality dependent on the size and our assessment of the risk of material misstatement of that component. In the audit of each component, we further applied performance materiality levels of 65% of the component materiality to our testing to ensure that the risk of errors exceeding component materiality was appropriately mitigated.

 

 

Reporting threshold

 

We agreed with the Audit Committee that we would report to them misstatements identified during our audit above £1,600 for the both the Group and £1,000 Company audit as well as misstatements below those amounts that, in our view, warranted reporting for qualitative reasons.

 

Other information

We have nothing to report in this regard.

Opinions on other matters prescribed by the Companies Act 2006

In our opinion, based on the work undertaken in the course of the audit:

·    the information given in the strategic report and the directors' report for the financial year for which the financial statements are prepared is consistent with the financial statements; and

·    the strategic report and the directors' report have been prepared in accordance with applicable legal requirements.

 

Matters on which we are required to report by exception

 

In the light of the knowledge and understanding of the group and Company and its environment obtained in the course of the audit, we have not identified material misstatements in the strategic report or the directors' report.

We have nothing to report in respect of the following matters in relation to which the Companies Act 2006 requires us to report to you if, in our opinion:

·    adequate accounting records have not been kept by the Group and Company, or returns adequate for our audit have not been received from branches not visited by us; or

·    the Group and Company financial statements are not in agreement with the accounting records and returns; or

·    certain disclosures of directors' remuneration specified by law are not made; or

·    we have not received all the information and explanations we require for our audit.

Responsibilities of directors

 

As explained more fully in the Statement of Directors' responsibilities statement set out on page 19, the directors are responsible for the preparation of the financial statements and for being satisfied that they give a true and fair view, and for such internal control as the directors determine is necessary to enable the preparation of financial statements that are free from material misstatement, whether due to fraud or error.

In preparing the financial statements, the directors are responsible for assessing the Group's and Company's ability to continue as a going concern, disclosing, as applicable, matters related to going concern and using the going concern basis of accounting unless the directors either intend to liquidate the Group or the Company or to cease operations, or have no realistic alternative but to do so.

 

Auditor's responsibilities for the audit of the financial statements

 

The objectives of our audit, in respect to fraud are; to identify and assess the risks of material misstatement of the financial statements due to fraud; to obtain sufficient appropriate audit evidence regarding the assessed risks of material misstatements due to fraud, through designing and implementing appropriate responses; and to respond appropriately to fraud or suspected fraud identified during the audit. However, the primary responsibility for the prevention and detection of fraud rests with both those charged with governance of the entity and management.

Our audit procedures were primarily directed towards testing the accounting systems in operation upon which we have based our assessment of the financial statements for the year-ended 31 December 2025.

 

Our approach to identifying and assessing the risks of material misstatement in respect of irregularities, including fraud and non-compliance with laws and regulations, was as follows:

·    the engagement partner ensured the engagement team collectively had the appropriate competence, capabilities and skills to identify or recognise non-compliance with applicable laws and regulations in the United Kingdom;

·    we identified the laws and regulations applicable to the company through discussions with directors and other management, and from our knowledge and experience of the entity's activities.

·    we focused on specific laws and regulations which we considered may have a direct material effect on the financial statements or the operations of the company, including Companies Act 2006, taxation legislation, data protection, employment and health and safety legislation.

·    we assessed the extent of compliance with the laws and regulations identified above through making enquiries of management and reviewing legal expenditure; and

·    identified laws and regulations were communicated within the audit team regularly and the team remained alert to instances of non-compliance throughout the audit.

 

 

We assessed the susceptibility of the company's financial statements to material misstatement, including obtaining an understanding of how fraud might occur, by:

·    making enquiries of management as to where they considered there was susceptibility to fraud, their knowledge of actual, suspected and alleged fraud; and

·    considering the internal controls in place to mitigate risks of fraud and non-compliance with laws and regulations.

 

To address the risk of fraud through management bias and override of controls, we:

·    performed analytical procedures to identify any unusual or unexpected relationships;

·    tested journal entries to identify unusual transactions;

·    assessed whether judgements and assumptions made in determining the accounting estimates as disclosed in Note 2 of the financial statements were indicative of potential bias; and

·    investigated the rationale behind significant or unusual transactions.

 

In response to the risk of irregularities and non-compliance with laws and regulations, we designed procedures which included, but were not limited to:

·    reading the minutes of meetings of those charged with governance; and

·    enquiring of management as to actual and potential litigation and claims.

There are inherent limitations in our audit procedures described above. The more removed that laws and regulations are from financial transactions, the less likely it is that we would become aware of non-compliance.

 

Auditing standards also limit the audit procedures required to identify noncompliance with laws and regulations to enquiry of the directors and other management and the inspection of regulatory and legal correspondence, if any.

Material misstatements that arise due to fraud can be harder to detect than those that arise from error as they may involve deliberate concealment or collusion.

A further description of our responsibilities for the audit of the financial statements is located on the Financial Reporting Council's website at: http://www.frc.org.uk/auditorsresponsibilities.

This description forms part of our auditor's report.

Use of this report

This report, including the opinions, has been prepared for and only for the Company's members as a body in accordance with Chapter 3 of Part 16 of the Companies Act 2006 and for no other purpose. We do not, in giving these opinions, accept or assume responsibility for any other purpose or to any other person to whom this report is shown or into whose hands it may come save where expressly agreed by our prior consent in writing.

 

 

Talha Farrukh

Audit Partner

For and on behalf of Gerald Edelman LLP,

Senior Statutory Auditor

73 Cornhill

London United Kingdom

EC3V 3QQ

27 March 2026

 

 

Consolidated statement of comprehensive income

For the year ended 31 December 2025


 

 

 

 


Notes

 

Year ended

31 December

2025

Year ended

31 December

2024


 

 

£'000

£'000


 




Revenue from contracts with customers

3


2,732

1,883


 




Cost of sales

 


(1,250)

(886)


 


───────

───────

Gross Profit

 


1,482

997


 




Share based payment cost

 


(753)

(26)

Depreciation and amortisation

 


(54)

(68)

Other administrative costs

 


(1,910)

(1,755)


 




 Total administrative expenses

5


(2,717)

(1,849)

 

 


───────

───────

Operating loss

 


(1,235)

(852)


 





 





 


───────

───────

Loss before tax

 


(1,235)

(852)


 




Taxation

6


2

5


 


───────

───────

Loss for the period

 


(1,233)

(847)

 

 




Other comprehensive income

 



-

 

 


───────

───────

Total comprehensive loss for the period

 


(1,233)

(847)


 


═══════

═══════

Total comprehensive loss attributable to:

 




    Owners of the company

 


(1,233)

(847)


 





 


═══════

═══════

Earnings per share from continued operations

 




Basic profit/(loss) per share - pence

7


(0.78)p

(0.63)p

Diluted profit/(loss) per share - pence

 


(0.71)p

(0.61)p


 


═══════

═══════

 

 

All activities relate to continuing operations

 

Consolidated Statement of Financial Position as at 31 December 2025


 

 

 

 

 


 

Notes

 

As at

31 December 2025

As at

31 December 2024

ASSETS

 

 

 

£'000

£'000

Non-current assets

 

 




Intangibles

 

8


186

236

Property, plant and equipment

 

9


5

7


 

 


───────

───────

 

 

 


191

243

 

 

 


───────

───────

CURRENT ASSETS

 

 




Inventories

 

11


-

31

Trade and other receivables

 

12


351

257

Cash and cash equivalents

 

13


1,266

1,646


 

 


───────

───────

 

 

 


1,617

1,934


 

 


───────

───────

TOTAL ASSETS

 

 


1,808

2,177


 

 


═══════

═══════

EQUITY

 

 




Shareholders' Equity

 

 




Called up share capital

 

14


79

79

Share premium

 

15


4,534

4,534

Share based payment reserve

 

15


794

41

Group reorganisation reserve

 

15


(945)

(945)

Retained earnings

 

15


(3,019)

(1,786)


 

 


───────

───────

Total Equity

 

 


1,443

1,923

 

 

 


───────

───────

LIABILITIES

 

 




Current liabilities

 

 




Trade and other payables

 

16


318

194


 

 


───────

───────


 

 


318

194


 

 


───────

───────

Non - current liabilities

 

 




Deferred tax liability

 

17


47

60


 

 


───────

───────


 

 


47

60


 

 


───────

───────

TOTAL LIABILITIES

 

 


365

254

 

 

 


───────

───────

TOTAL EQUITY AND LIABILITIES

 

 


1,808

2,177


 

 


═══════

═══════

 

These financial statements were approved and authorised for issue by the Board of Directors on 30 March 2026 and were signed on its behalf by:

 

 

S Andersen

 

Director

Company Registration no. 13723211

 

 

Consolidated Statement of Changes in Equity

For the period ended 31 December 2025


 

Called up

Share capital

 

 

Share Premium

 

 

Share-based

Payment Reserve

Group Reorganisation

Reserve

 

 

Retained Earnings

 

 

Total

equity


£'000

£'000

£,000

£'000

£'000

£'000








As at 1 January 2024

61

3,338

57

(945)

(980)

1,531








Loss for the period

-

-

-

-

(847)

(847)








Forfeiture of share options

-

-

(41)

-

41

-








Share based payments

-

-

25

-

-

25








Share issue

18

1,208

-

-

-

1,226








Share issue costs


(12)




(12)


──────

───────

──────

──────

─────

───────

Balance at 31 December 2024

79

4,534

41

(945)

(1,786)

1,923








Loss for the period

-

-

-

-

(1,233)

(1,233)








Forfeiture of share options

-

-

-

-


-








Share based payment

-

-

753

-

-

753















Share issue

-

-

-

-

-

-








Share issue costs

-

-




-


──────

───────

──────

──────

─────

───────

Balance at 31 December 2025

79

4,534

794

(945)

(3,019)

1,443


══════

═══════

══════

══════

═════

═══════





























The notes form part of these financial statements

 

Consolidated Statement of Cash Flows

For the period ended 31 December 2025

 

 

 

 

Notes

 

Year ended

31 December 2025

Year ended

31 December 2024


 

 


 


£

£

 

 




Cash flows from operating activities

 





 




Cash utilised by operations

1


(367)

(1,060)


 





 


──────

──────

Net cash outflow from operating activities

 


(367)

(1,060)


 




 

 





 




Cash flows from investing activities

 





 




Acquisition of property, plant and equipment

 


(12)

(10)


 





 





 


──────

──────

Net cash outflow from investing activities

 


(12)

(10)


 


──────

──────

Cash flows from financing activities

 




Share issues net of issue costs

 


-

1,214


 





 


──────

──────

Net cash inflow from financing activities

 


-

1,214


 


──────

──────


 




 

 




 

 




Increase/(decrease) in cash and equivalents

 


(380)

144


 




Cash and cash equivalents at beginning of period

 


1,646

1,502


 





 


──────

──────

Cash and cash equivalents at end of period

2


1,266

1,646


 


══════

══════

 

 




 

 

Notes to the Consolidated Statement of Cash Flows

For the period ended 31 December 2025

 

1.   Reconciliation of loss before income tax to cash outflow from operations

     

 

Year ended

31 December

2025

Year ended

31 December

2024

 

£'000

£'000

 

 

 

Operating loss

(1,235)

(852)

Share based payments

753

26

Decrease/(Increase) in inventories

31

72

(Increase)/Decrease in trade and other receivables

(94)

8

Increase/ (Decrease) in trade and other payables

123

(381)

Amortisation of patents and development costs

50

50

Depreciation

4

3

Write off intangible assets

(9)

14


──────

──────

Net cash outflow from operations

(377)

(1,060)


══════

══════

 

2.   Cash and Cash Equivalents

 

 

Year ended

31 December  2025

 

Year ended

31 December  2024

 

                            £    

                            £    

Cash and cash equivalents

1,266

1,646


════════

════════







 

Company Statement of Financial Position

As at 31 December 2025

 


Notes

 

As at

31 December 2025

As at

31 December 2024

ASSETS

 

 

£'000

£'000

Non-current assets

 




Investments

10


54

54


 


───────

───────

 

 


54

54

 

 


───────

───────

CURRENT ASSETS

 




Trade and other receivables

12


55

56

Cash and cash equivalents

13


25

793


 


───────

───────

 

 


80

849


 


───────

───────

TOTAL ASSETS

 


134

903


 


═══════

═══════

EQUITY

 




Shareholders' Equity

 




Called up share capital

14


79

79

Share premium

15


4,534

4,534

Share based payment reserve

15


794

41

Retained earnings

15


(5,328)

(3,848)


 


───────

───────

Total Equity

 


79

806

 

 


───────

───────

LIABILITIES

 




CURRENT LIABILITIES

 




 

 




Trade and other payables

16


55

97


 


───────

───────

TOTAL LIABILITIES

 


55

97

 

 


───────

───────

 

 




TOTAL EQUITY AND LIABILITIES

 


134

903


 


═══════

═══════

 

The Company has elected to take the exemption under section 408 of the Companies Act 2006 not to present the parent Company income statement account.

 

The loss for the parent Company for the year was £1.480m (2024: £0.96m).

 

These financial statements were approved and authorised for issue by the Board of Directors on 27 March 2026 and were signed on its behalf by:

 

 

S Andersen

Director

Company Registration no. 13723211

 

 

Company Statement of Changes in Equity

For the period ended 31 December 2025


 

Called up

Share capital

 

 

Retained Earnings

 

 

Share

Premium

Share-based

Payment reserve

 

 

Total

equity


£'000

£'000

£'000

£'000

£'000







As at 1 January 2024

61

(2,933)

3,338

57

523







Loss for the year

-

(956)

-

-

(956)







Forfeiture of share options

-

41

-

(41)

-







Share based payments

-

-

-

25

25







Share issue

18

-

1,208

-

1,226







Share issue costs

-

-

(12)

-

(12)


──────

───────

──────

──────

─────

Balance at 31 December  2024

79

(3,848)

4,534

41

806







Loss for the year

-

(1,480)

-

-

(1,480)







Forfeiture of shares

-

-

-

-

-







Share based payments

-

-

-

753

753







Share issue

-

-

-

-

-







Share issue costs

-

-

-

-

-








──────

───────

───────

──────

───────

Balance at 31 December 2025

79

(5,328)

4,534

794

79


══════

═══════

═══════

══════

═══════

 

 

 

Company Statement of Cash Flows

For the period ended 31 December 2025

 


Notes

 

 

Year ended

31 December 2025

 

Year ended

31 December 2024


 

 


 


£'000

£'000

 

 




Cash flows from operating activities

 





 




Cash utilised by operations

1


(1,300)

(1,122)


 


───────

───────

Net cash outflow from operating activities

 


(1,300)

(1,122)


 




Cash flows from financing activities

 





 




Share issues net of issue costs

 


-

1,214


 


───────

───────

Net cash inflow from financing activities

 


-

1,214


 


───────

───────


 




Cash flows from investing activities

 




 

 




Net amounts advanced to subsidiary  

 


532

228

 

 


───────

───────

Net cash inflow from investing activities

 


532

228

 

 


───────

───────

 

 




Increase/(decrease) in cash and equivalents

 


(768)

320


 




Cash and cash equivalents at beginning of period

 


793

473


 


───────

───────

Cash and cash equivalents at end of period

2


25

793


 


═══════

═══════

 

 




 

 

Notes to the Company Statement of Cash Flows

For the period ended 31 December 2025

 

 

1.   Reconciliation of loss before income tax to cash generated from operations

 

 

 

Year ended

31 December 2025

 

Year ended

31 December 2024

 

£'000

£'000

 

 

 

Operating (loss)/Profit

(1,480)

(956)

Share based payment expense

753

26

Increase in trade and other receivables

1

21

Loan (from)/to subsidiary written off

(532)

(228)

(Decrease)/Increase in trade and other payables

(42)

15





──────

──────

Net cash outflow from operations

(1,300)

(1,122)


══════

══════




 

2.   Cash and Cash Equivalents

 

 

As at

31 December 2025

As at

31 December 2024

 

                            £'000    

                            £'000    




Cash and cash equivalents

25

793


═══════

═══════

 

 

 

Notes to the Consolidated and Company Financial Statements

(Continued)

 

For the year ended 31 December 2025

 

1.   General Information

     

ProBiotix Health plc is a Public Limited Company limited by shares incorporated and domiciled in England and Wales. Details of the registered office, the officers and advisers to the Company are presented on the company information page at the start of this report. The Company's offices are at First Floor Zucchi Suite, Nostell Business Estate, Wakefield, England, WF4 1AB. The Company is listed on the AQSE Growth Market .

 

The functional currency of the Group is GBP.

 

The principal activity is that of developing probiotics to tackle cardiovascular disease and other lifestyle conditions which are affecting growing numbers of people across the world.

 

These financial statements present the results and balances of the Company and its subsidiaries (together, the 'Group') for the year ended 31 December 2025.

 

 

2.   Accounting Policies

     

      Statement of compliance

The consolidated financial statements of Probiotix Health Plc have been prepared in accordance with UK adopted international accounting standards and the Companies Act 2006 applicable to companies reporting under UK adopted international accounting standards  

 

Basis of consolidation

The consolidated financial statements incorporate the financial statements of the Company and entities controlled by the Company (its subsidiaries) made up to 31 December each year.   The group controls an investee when it is exposed, or has rights, to variable returns from its involvement with the investee and has the ability to affect those returns through its power over the investee.

The results of subsidiaries acquired or disposed of during the year are included in the consolidated statement of comprehensive income from the effective date of acquisition or up to the effective date of disposal, as appropriate.

Where necessary, adjustments are made to the financial statements of subsidiaries to bring their accounting policies into line with those used by other members of the Group.

All intra-group transactions, balances, income and expenses are eliminated on consolidation.

Changes in the Group's ownership interests in subsidiaries that do not result in the Group losing control over the subsidiaries are accounted for as equity transactions. The carrying amounts of the Group's interests and the non-controlling interests are adjusted to reflect the changes in their relative interests in the subsidiaries. Any difference between the amount by which the non-controlling interests are adjusted and the fair value of the consideration paid or received is recognised directly in equity and attributed to owners of the Company.

 

When the Group loses control of a subsidiary, the profit or loss on disposal is calculated as the difference between (i) the aggregate of the fair value of the consideration received and the fair value of any retained interest and (ii) the previous carrying amount of the assets (including goodwill), and liabilities of the subsidiary and any non-controlling interests. Where certain assets of the subsidiary are measured at revalued amounts or fair values and the related cumulative gain or loss has been recognised in other comprehensive income and accumulated in equity, the amounts previously recognised in other comprehensive income and accumulated in equity are accounted for as if the Company had directly disposed of the related assets (i.e. reclassified to profit or loss or transferred directly to retained earnings).

 

The fair value of any investment retained in the former subsidiary at the date when control is lost is regarded as the fair value on initial recognition for subsequent accounting under IFRS 9 "Financial Instruments: Recognition and Measurement" or, when applicable, the cost on initial recognition of an investment in an associate or a jointly controlled entity.

 

      Basis of preparation

 

The financial statements have been prepared under the historical cost convention. The functional and presentational  currency is GBP rounded to the nearest thousand.

 

The principal accounting policies are summarised below. They have all been applied consistently throughout the period under review.

 

 

2.   Accounting Policies (continued)

 

Going concern

 

The financial statements have been prepared on the assumption that the Group is a going concern. When assessing the foreseeable future, the Directors have looked at the Cash forecast for the next 12 months from the date of this report, the cash at bank available as at the date of approval of this report and are satisfied that the Group should be able to cover its committed  cost, and  other administrative expenses, as well as its ongoing research and development expenditure as they fall due.

 

After assessing the current loss making position, plausible  downside scenarios, and based on strong revenue and forecasts, the directors have a reasonable expectation that the Group and the Company  have adequate resources to continue in operational existence for the foreseeable future. Accordingly, they continue to adopt a going concern basis in preparing the annual report and financial statements.

 

 

  Standards, amendments and interpretations effective and adopted in FY 2025

 

The accounting policies adopted are consistent with those of the previous financial year, except for the adoption of amendments effective for annual periods beginning on or after 1 January 2025. In the current year, the Group adopted Lack of Exchangeability (Amendments to IAS 21), which became effective for annual reporting periods beginning on or after 1 January 2025. The adoption of this amendment did not have a material impact on the Group's consolidated financial statements.

 

Standards, amendments and interpretations issued/adopted but not yet effective


The Group has not early adopted any standard, amendment or interpretation that has been issued and adopted, but is not yet effective as at 31 December 2025. These include Amendments to the Classification and Measurement of Financial Instruments (Amendments to IFRS 9 and IFRS 7), Annual Improvements to IFRS Accounting Standards-Volume 11, and Contracts Referencing Nature-dependent Electricity (Amendments to IFRS 9 and IFRS 7), each effective for annual reporting periods beginning on or after 1 January 2026. The Group is currently assessing the impact of these amendments on its consolidated financial statements.

 

 

2.   Accounting Policies (continued)

 

New standards and interpretations not yet adopted

 

The International Accounting Standards Board (IASB) has issued the following standards, amendments and interpretations with an effective date after the date of these consolidated financial statements. These are effective for annual reporting periods beginning on or after the date indicated:

 

 

Standard/ amendment

When issued

Effective date (early application is possible unless otherwise noted)

Standards/ Interpretations amended

Standard withdrawn

IFRS 18
Presentation and
Disclosure in Financial
Statements

April 2024

01 January 2027

IFRS 1, IFRS 3, IFRS 5, IFRS 6, IFRS 7, IFRS 8, IFRS 9, IFRS 12, IFRS 13, IFRS 14, IFRS 15, IFRS 16, IFRS 17, IAS 2, IAS 7, IAS 8, IAS 10, IAS 12, IAS 16, IAS 19, IAS 20, IAS 21, IAS 24, IAS 28, IAS 29, IAS 32, IAS 33, IAS 34, IAS 38, IAS 40, IAS 41, IFRIC 1, IFRIC 14, IFRIC 17, IFRIC 19, IFRIC 23, SIC-32

IAS 1

IFRS 19 Subsidiaries without Public Accountability: Disclosures

May 2024

01 January 2027

IFRS 1, IFRS 5, IFRS 13, IFRS 17, IFRS 18, IAS 32, IAS 34, IFRIC 14


Amendments to the Classification and Measurement of Financial Instruments Amendments to IFRS 9 and IFRS 7

May 2024

01 January 2026

IFRS 7, IFRS 9, IFRS 19


Annual Improvements
to IFRS Accounting
Standards-Volume 11

July 2024

01 January 2026

IFRS 1, IFRS 7,
IFRS 9, IFRS 10,
IAS 7


Contracts referencing Nature-dependent Electricity Amendments to IFRS 9 and IFRS 7

December 2024

01 January 2026

IFRS 7, IFRS 9


 

 

2.   Accounting Policies (continued)

 

The Group is assessing the impact of these new standards and the Group's financial reporting will be presented in accordance with these standards from the effective date.

 

There are no other standard interpretations that are not yet effective that would be expected to have a material impact on the Group.

The Directors anticipate that the adoption of these standards and the interpretations in future period will have no material impact on the financial statements of the company.

 

2.   Accounting Policies (continued)

 

2.1 Revenue recognition

Revenue is measured at the fair value of sales of goods and services less returns and sales taxes.  The Group has analysed its business activities and applied the five-step model prescribed by IFRS 15 to each material line of business, as outlined below:

2.1.1 Sale of products  

Revenue is recognised at a point in time for sales of products and licensing.

The contract to provide a product is established when the customer places a purchase order. The performance obligation is to provide the product requested by an agreed date, and the transaction price is the value of the product as stated in our order acknowledgement.  The performance obligation is typically met when the product is made available for collection by the customer so revenue is primarily recognised for each product when notification of availability is communicated to the customer.

 

2.   Accounting Policies (continued)

        2.1. License arrangements

Revenue is recognised when the customer obtains control of the rights to use the IP. The performance obligations are considered to be distinct from any ongoing distribution arrangements which are treated in line with sales of products.

 

2.2 Investments

Investments in subsidiaries and joint ventures are stated at cost less, where appropriate, provisions for impairment. The Company tests the investment balances for impairment annually or when there are indicators of impairment

2.3 Taxation

      Income tax expense represents the sum of the tax currently payable and deferred tax.

(i)   Current tax

 

            Current taxes are based on the results shown in the financial statements and are calculated according to local tax rules using tax rates enacted or substantially enacted by the statement of financial position date.

 

            Income tax is recognised in the income statement or in equity if it relates to items that are recognised in the same or a different period, directly in equity.

 

            Current tax assets and liabilities for the current and prior periods are measured at the amount expected to be recovered from or paid to the taxation authorities.

 

(ii)  Deferred tax

 

            Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between the tax base of assets and liabilities and their carrying amounts for financial reporting purposes.

 

      Deferred tax liabilities are recognised for all taxable temporary differences.

 

            Deferred tax assets are recognised for all deductible temporary differences, carry forward of unused tax assets and unused tax losses, to the extent that it is probable that taxable profit will

 

            be available against which the deductible temporary differenced and the carrying forward or unused tax assets and unused tax losses can be utilised.

 

            The carrying amount of deferred tax assets is reviewed at each balance sheet date and reduced to the extent that it is no longer probable that sufficient taxable profit will be available to allow all or part of the deferred tax assets to be utilised. Conversely, previously unrecognised deferred tax assets are recognised to the extent that it is probable that sufficient taxable profit that sufficient taxable profit will be available to allow all or part of the deferred tax asset to be utilised.

 

            Deferred tax assets and liabilities are measured at the tax rates that are expected to apply to the year when the asset is realised or the liability is settled, based on the tax rates and tax laws that have been enacted or substantively enacted at the balance sheet date.

 

2.   Accounting Policies (continued)

 

2.4 Financial instruments

      Financial assets and financial liabilities are recognised when the group becomes a party to the contractual provisions of the instrument.

 

Loans and receivables are initially measured at fair value and are subsequently measured at amortised cost using the effective interest rate method.

 

Trade receivables are initially measured at fair value and are subsequently measured at amortised cost less appropriate provisions for estimated irrecoverable amounts. Such provisions are recognised in the statement of income.

 

Cash and cash equivalents comprise cash in hand and demand deposits and other short-term highly liquid investments with maturities of three months or less at inception that are readily convertible to a known amount of cash and are subject to an insignificant risk of changes in value.

 

Trade payables are not interest-bearing and are initially valued at their fair value and are subsequently measured at amortised cost.

 

2.5 Equity instruments are recorded at fair value, being the proceeds received, net of direct issue costs.

2.6 Share Capital - Ordinary shares are classified as equity. Incremental costs directly attributable to the issue of new shares or options are shown in equity as a deduction, net of taxation, from the proceeds.

 

2.7 Inventory

Inventories are stated at the lower of cost and net realisable value. Cost is determined using the first-in, first-out (FIFO) method. Net realisable value is the estimated selling price in the ordinary course of business, less applicable variable selling expenses.

 

2.   Accounting Policies (continued)

 

2.8 Impairment of non-financial assets

At each statement of financial position date, the Group reviews the carrying amounts of its investments to determine whether there is any indication that those assets have suffered an impairment loss. If any such indication exists, the recoverable amount of the asset is estimated in order to determine the extent of the impairment loss (if any). Where the asset does not generate cash flows that are independent from other assets, the group estimates the recoverable amount of the cash-generating unit to which the asset belongs. An intangible asset with an indefinite useful life is tested for impairment annually and whenever there is an indication that the asset may be impaired.

 

Recoverable amount is the higher of fair value less costs to sell and value in use. In assessing value in use, the estimated future cash flows are discounted to their present value using a pre-tax discount rate that reflects current market assessments of the time value of money and the risks specific to the asset for which the estimates of future cash flows have not been adjusted.

 

If the recoverable amount of an asset (or cash-generating unit) is estimated to be less than its carrying amount, the carrying amount of the asset (cash-generating unit) is reduced to its recoverable amount. An impairment loss is recognised as an expense immediately, unless the relevant asset is carried at a re-valued amount, in which case the impairment loss is treated as a revaluation decrease.

 

Where an impairment loss subsequently reverses, the carrying amount of the asset (cash-generating unit) is increased to the revised estimate of its recoverable amount, but so that the increased carrying amount does not exceed the carrying amount that would have been determined had no impairment loss been recognised for the asset (cash-generating unit) in prior years. A reversal of an impairment loss is recognised as income immediately, unless the relevant asset is carried at a revalued amount, in which case the reversal of the impairment loss is treated as a revaluation increase.

 

2.9 Capital management

      Capital is made up of stated capital, premium, other reserves and retained earnings. The objective of the Group's capital management is to ensure that it maintains strong credit ratings and capital ratios. This will ensure that the business is correctly supported and shareholder value is maximised.

 

      The Group manages its capital structure through adjustments that are dependent on economic conditions. In order to maintain or adjust the capital structure, the Company may choose to issue new share capital to shareholders.  There were no changes to the objectives, policies or processes during the period ended 31 December 2025.

     

2.   Accounting Policies (continued)

 

2.10 Share-based compensation

The fair value of the employee and suppliers services received in exchange for the grant of the options is recognised as an expense. The total amount to be expensed over the vesting period is determined by reference to the fair value of the options granted, excluding the impact of any non-market vesting conditions (for example, profitability and sales growth targets). Non-market vesting conditions are included in assumptions about the number of options that are expected to vest. At each statement of financial position date, the entity revises its estimates of the number of options that are expected to vest. It recognises the impact of the revision to original estimates, if any, in the income statement, with a corresponding adjustment to equity.

The proceeds received net of any directly attributable transaction costs are credited to share capital (nominal value) and share premium when the options are exercised.

The fair value of share-based payments recognised in the income statement is measured by use of the Black Scholes model, which takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model is adjusted; based on management's best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. The share price volatility percentage factor used in the calculation is based on management's best estimate of future share price behaviour and is selected based on past experience, future expectations and benchmarked against peer companies in the industry.

 

2.11 Intangibles - Patents and Trademarks

Separately acquired patents are shown at historical cost. Patents have a finite useful life and are carried at cost less accumulated amortisation. Amortisation is calculated using the straight line method to allocate the cost of the patents over their estimated useful life of ten years once the patents have been granted.

 

      2.12 Research and Development

Research expenditure is written off to the statement of comprehensive income in the year in which it is incurred. Development expenditure is written off in the same way unless the Directors are satisfied as to the technical, commercial and financial viability of individual projects. In this situation, the expenditure is deferred and amortised over the 10 years during which the Company is expected to benefit.

 

      2.13 Critical accounting judgments and key sources of estimation uncertainty

The preparation of the financial statements requires management to make estimates and assumptions concerning the future that affect the reported amounts of assets and liabilities and the disclosure of contingent assets and liabilities at the dates of the financial statements and the reported amounts of revenues and expenses during the reporting period.

 

2.   Accounting Policies (continued)

 

The resulting accounting estimates will, by definition, differ from the related actual results.

 

·    Share based payments

The fair value of share based payments recognised in the income statement is measured by use of the Black Scholes and Monte Carlo models which takes into account conditions attached to the vesting and exercise of the equity instruments. The expected life used in the model is adjusted; based on management's best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations. The share price volatility percentage factor used in the calculation is based on management's best estimate of future share price behaviour and is selected based on past experience, future expectations and benchmarked against peer companies in the industry.

 

·    Amortisation

Management have estimated that the useful life of  the patent development costs that have been capitalised in line with the recognition criteria of IAS38 have been estimated to have a useful economic life of 10 years . Research and developments that have been capitalised in line with the recognition criteria of IAS38 have been estimated to have a useful economic life of 10 years. These estimates are reviewed annually and revised if the useful life is deemed to be lower based on the trading business or any changes to patent law.

 

·      Impairment reviews

UK adopted international accounting standards requires management to undertake an annual test for impairment of indefinite lived assets and, for finite lived assets to test for impairment if events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Impairment testing is an area involving management judgement, requiring assessment as to whether the carrying value of assets can be supported. In calculating the net present value of the future cash flows involved in the impairment assessment, certain assumptions are required to be made in respect of highly uncertain matters. Assets under consideration are intangible assets on a Group level and investments on the Company level.

3.   Segmental Reporting

 

In the opinion of the directors, the Group has one class of business, in three geographical areas being that of identifying and developing microbial strains, compounds and formulations for use in the nutraceutical industry. The Group sells into three highly interconnected markets, all costs assets and liabilities are derived from the UK location.

 

 

Revenue analysed by geographical market

 

 

 

Year ended

31 December   2025

 

Year ended

31 December 2024

 

£'000

£'000

UK

61

34

US

1,810

1,457

Rest of world

861

392




 

──────

──────

 

2,732

1,883

 

══════

══════

 

During the reporting period one customer represented £1.7m, (62.2%) of Group revenues. (2024: one customer generated £1.4m representing 74.3% of Group revenues)

 

4.   Employees and Directors

 

 

 

 Year ended

31 December 2025

 

 Year ended

31 December 2024

 

£'000

£'000

Wages and salaries  

690

472

Directors' remuneration

264

272

Directors' fees

123

104

Social security costs

2

13

Pension costs

71

62

 

──────

──────

 

1,150

923

 

══════

══════

 

Wages and salaries of £NIL (2024: £89k) represent a recharge of salaries from Optibiotix Health PLC for employees who are under employment contracts with Optibiotix and recharged under a share services agreement.

 

 

 

 

 

 Year ended

31 December 2025

 

 Year ended

31 December 2024

 

No.

No.

The average monthly number of employees during the period was as follows:


 

 




Group



Directors

5

4




Selling, General and Administration

7

4


──────

──────


12

8

 

══════

══════

Company

 

 

Directors

5

4


──────

──────


5

4


══════

══════

 

 

 

 

 

Year ended

31 December 2025

 

Year ended

31 December 2024


£

£

Directors' remuneration (See table above)*

387

376







Pension

13

12


──────

──────

Total emoluments

400

388


══════

══════

      *Share based payments not included

 

4.   Employees and Directors (continued)

 


Year ended

31 December 2025

      Year ended

31 December 2024


£'000

£'000

Emoluments paid to the highest paid director






Remuneration for qualifying services

264

241




Company pension contributions to defined scheme

13

12





──────

──────


277

253


══════

══════

 

 

There are no key management personnel other than the directors of the company.

 

The number of directors to whom defined contribution pension benefits accrue is 1. No directors exercised share options in the year. 

 

Directors' remuneration

 

Details of emoluments received by Directors of the Group for the year ended 31 December 2025 are as follows:


Remuneration

 

Share based

Pension Costs

Total


and fees

Bonuses

payments

 

 


£'000

£'000

£'000

£'000

£'000

A Reynolds*

60

-

77

-

137

S Andersen*

264

-

198

13

475

S P O'Hara*

21

-

232

-

253

M Caspani*

21

-

-

28

F Bruhn-Petersen*

21

-

-

-

21

Total

387

-

514

13

914

 

      *For disclosure in relation to directors' fees please refer to Note 18.

 

     **Share based payments is an accounting charge and not remuneration paid to directors.

 

4.   Employees and Directors (continued)

 

Details of emoluments received by Directors of the Group for the year ended 31 December 2024 are as follows:


Remuneration

 

Share based

Pension Costs

Total


and fees

Bonuses

payments

 

 


£'000

£'000

£'000

£'000

£'000

A Reynolds

54

-

-

-

54

S Andersen

241

-

-

12

253

S P O'Hara

30

-

-

-

30

M Caspani

20

-

-

38

M Hvid-Hansen

26

-

-

-

26

F Bruhn-Petersen

5

-

-

-

5

Total

376

-

18

12

406

 

 

5.   Expenses - analysis by nature


 

Year ended 31 December

2025

 

Year ended

31 December

2024


£'000

£'000




Research and development

24

28

Directors' fees & remuneration (Note 4)*

387

376

Salaries

690

472

Pension Costs

71

62

Auditor remuneration - audit fees (Group and Company accounts) 

42

38

Brokers & Advisors

156

139

Share based payments

753

26

Advertising & marketing

120

121

Amortisation and depreciation

55

68

Legal and professional fees

146

231

Insurance

14

16

Rent

50

28

FX

(3)

13

Printing and stationery

11

16

Computer running costs

26

27

Travel costs

135

82

Other expenses

40

106


──────

──────

Total administrative expenses

2,717

1,849

 

 

 

══════

══════

 

6. Corporation Tax  

 

           

Year ended

31 December 2025

Year ended

31 December 2024


£'000

£'000




Current corporation charge

3

9

Foreign Tax

7

-

Deferred tax movement

(12)

(13)


──────

──────

Total taxation

2

(5)


══════

══════

 

Analysis of tax expense

     

      No liability to UK corporation tax arose on ordinary activities for the year ended 31 December 2025 nor for the period ended 31 December 2024.

 


 

Year ended

31 December 2025

 

Year ended

31 December 2024


£'000

£'000




Profit (Loss) on ordinary activities before income tax

(1,238)

(852)


═══════

═══════




Loss on ordinary activities multiplied by the effective rate of corporation tax in UK of 25% (2024:25%)

(310)

 

(213)




Effects of:



Disallowables

124

11

Income not taxable

(125)

-

Amortisation

25

13

Losses utilised

283

(104)

Unused tax losses carried forward

-

(302)


──────

──────

Total

2

9


══════

══════

 

 

 

The Group has estimated losses of £3.692m (2024: £2.477m) which can be carried forward to be utilised against future profits.

 

 

The tax losses have resulted in a deferred tax asset at 25% of approximately £1.27m (2024: £0.62m) which has not been recognized as it is uncertain whether future taxable profits will be sufficient to utilise the losses.             

 

7.   Earnings per share

 

      Basic earnings per share is calculated by dividing the earnings attributable shareholders by the weighted average number of ordinary shares outstanding during the period.

 

      Reconciliations are set out below:

 

 

Basic and diluted EPS

 

 

Earnings

2025

Weighted average

Number of shares

 

 

Profit per-share


£'000

No.

Pence





Basic EPS

(1,233)

158,166,666

(0.78)

Diluted EPS

(1,233)

172,916,666

(0.71)


══════

════════

══════






 

 

Earnings

2024

Weighted average

Number of shares

 

 

Profit per-share


£'000

No.

Pence





Basic EPS

(847)

133,466,666

(0.63)

Diluted EPS

(847)

138,966,666

(0.61)


══════

════════

══════

     

As at 31 December 2025 there were 14,750,000 (2024: 5,500,000) outstanding share options. These are non-dilutive due to the losses incurred in the year.

 

Intangible assets

 

 

Development Costs and Patents

 

£'000

Cost


At 1 January 2024

524

Write off

(18)


───────

At 31 December 2024

506




───────

At 31 December 2025

506


═══════



Amortisation


At 31 December 2023

223

Amortisation charge for the year

50

Amortisation eliminated on write off

(6)


───────

At 31 December 2024

267

Amortisation charge for the year

53

Amortisation eliminated on write off


 

───────

At 31 December 2025

320

 

═══════

 


Carrying amount

 

 

At 31 December 2025

186

At 31 December 2024

236


═══════

 

All intangible assets relate to the group's principal activities.

 

The company had no intangible assets.

 

9. Property, plant and equipment

 

 

 

Fixtures and fittings

Computer equipment

Total

 

£'000

£'000

£'000

Cost




At 1 January 2024

1

8

9

Additions

1

2

3

Disposals





───────

───────

───────

At 31 December 2025

2

10

12


═══════

═══════

═══════





Depreciation




At 1 January  2024

0

2

2

Depreciation charge for the year

1

4

5

Depreciation eliminated on disposal




 

───────

───────

───────

At 31 December 2025

1

6

7

 

═══════

═══════

═══════

 




Carrying amount

 

 



At 31 December 2025

1

4

5

At 31 December 2024

1

6

7


═══════

═══════

═══════

 

 

 

 

10. Investments

 


2025

2024

 

£'000

£'000

Investments



At the beginning of the period

54

54




Additions


-







At 31 December

54

54

 

 

 

As at 31 December 2025 the Company directly held the following subsidiaries:

 

Name of company

Nature of

Business

Active /

Dormant

Country of incorporation

and place of business

Proportion of

equity interest

 

 





Probiotix Limited

Health Foods

Active

United Kingdom

100% of ordinary shares






Probiotix Health Denmark Aps

Health Foods

Active

Denmark

100% of ordinary shares






The registered office of Probiotix Limited is the same as the company.

 

Probiotix Health Denmark Aps   was registered 6 February 2023, the registered office is Transformervej 14 2860 Søborg, Denmark.

 

The Company acquired its 100% interest in Probiotix Limited by way of a share for share exchange on 11 February 2022.  Impairment indicators assess and none noted.

 

 

11. Inventories

 

Group

Company

 

2025

2024

2025

2024

 

£'000

£'000

£

£


───────

───────

───────

───────

Finished goods

-

31

-

-


══════

══════

══════

══════






 

      During the period £1.250m (2024: £0.882m) has been expensed to the income statement.

 

12. Trade and other Receivables

 

 

 

 

 

        Group

Company

 

2025

2024

2025

2024

 

£'000

£'000

£'000

£'000

 

 



 

Accounts receivable

196

141

-

-

Amount due from subsidiary

-

-

33

-

Other receivables

126

99

18

40

Prepayments

29

17

4

16


─────

─────

─────

─────


351

257

55

56


══════

══════

══════

══════

 

 

See note 19 in respect of the group's credit risk assessment.

 

 

13. Cash and Cash Equivalents

 

Group

Company

 

2025

2024

2025

2024

 

£'000

£'000

£'000

£'000






Cash and bank balances

1,266

1,646

25

793


══════

══════

══════

══════

 

 

14. Share Capital

 

 

 

2025

£'000

2024

£'000


──────

──────

Allotted, called up and fully paid share capital

79

79


══════

══════

 

 

Shares in issue

2025

 

2024

 




Opening balance 1 January

158,166,666

121,666,666




Share issue

-

36,500,000


──────

──────

Closing balance at 31 December

158,166,666

158,166,666


══════

══════

 

 

Share Capital

2025

£'000

2024

£'000




Opening balance 1 January

79

60




Share issue

-

19


──────

──────

Closing balance at 31 December

79

79


══════

══════

 

 

Share Premium

2025

£'000

2024

£'000




Opening balance 1 January

4,534

3,338




Share issue

-

1,196


──────

──────

Closing balance at 31 December

4,534

4,534


══════

══════

 

On 4 November 2021 the Company was incorporated with 1 share of £1.

 

On 7 February 2022 the £1 share capital was converted into 2,000 Ordinary shares of £0.0005 each.

 

On 4 March 2022, 99,998,000 Ordinary shares of £0.0005 were issued to acquire the whole share capital of Probiotix Limited.

 

On 31 March 2022. 9,761,904 Ordinary shares of £0.0005 were issued in settlement of convertible loan notes which automatically converted to shares on IPO at a conversion rate based on 50% of the IPO price.  

 

On 31 March 2022, 11,904,762 Ordinary shares of £0.0005 were issued at 21p a share in respect of a placing and subscription.   

 

On 3 September 2024. 36,500,000 Ordinary shares of £0.0005 were issued at 3p a share in respect of a placing and subscription.   

 

 

15.  Reserves

 

Share capital is the amount subscribed for shares at nominal value. Share premium represents amounts subscribed for share capital in excess of nominal value, net of expenses.

 

Group reorganisation reserve arises from the 100% acquisition of ProBiotix Limited on 31 March 2022 whereby the excess of the nominal value of the issued ordinary share capital issued over the net liabilities acquired is transferred to this reserve.

 

At 31 March 2022 Probiotix Health Plc investment in Probiotix Limited was £50k and the net liabilities acquired were £995K, resulting in the recognition of a group reorganisation reserve of £945k.

 

Retained earnings represents the cumulative profits and losses of the group attributable to the owners of the company.

 

Share based payment reserve represents the cumulative amounts charged in respect of unsettled options issued.

 

No dividends are proposed in respect of the period.

 

16.      Trade and other payables

 

Current:

 

 


    Group 

Company


2025

2024

2025

2024


£'000

£'000

£'000

£'000






Accounts Payable

238

25

-

11

-     Accrued expenses

72

60

55

43

-     Corporation tax payable

-

9

-

-

-     Other payables

8

100

-

-

-     Amount due to subsidiary

-

-

-

44


───────

───────

───────

───────

Total trade and other payables

318

194

55

97

 

══════

══════

══════

══════

 

The increase in accounts payable at the year end compared to 2024 is due to the timing and payment of invoices for the manufacture of products.

 

All payables are due within 12 months.

 

17. Deferred Tax

 

Deferred tax is provided, using the liability method, on temporary differences at the statement of financial position date between the tax base of assets and liabilities and their carrying amounts for financial reporting purposes.

 

Deferred tax is calculated in full on temporary differences under the liability method using a tax rate of 25% (2024: 25%).

 

The movement on the deferred tax account is as shown below:

 


2024

2024

 

£'000

£'000




At 31 December

60

75

Movement in the period

(13)

(15)


──────

──────

At 31 December

47

60


══════

══════

 

The deferred tax liability relates to timing differences in respect of tax treatment of intangible assets.

 

Deferred tax assets have not been recognised in respect of tax losses and other temporary differences giving rise to deferred tax assets as the directors believe there is uncertainty whether the assets are recoverable.

 

 

 

18. Related Party Disclosures

 

Group

 

During the year to 31 December 2025 £60,000, (2024: £54,165) was paid to Reyco Limited for the services of Adam Reynolds as Director of ProBiotix Health Plc. The balance owing at year end was NIL

 

During the year to 31 December 2025 £21,000, (2024: £20,000) was paid to Marco Caspani for his services as Director of ProBiotix Health plc. The balance owing at year end was NIL

 

During the year to 31 December 2025 £21,000, (2024: £5,000) was paid to Frederick Bruhn-Petersen for his services as Director of ProBiotix Health plc. The balance owing at year end was NIL

 

During the year to 31 December 2025 £21,000, (2024: £30,000) was invoiced by Optibiotix Health Plc for the services of Stephen O'Hara as Director of ProBiotix Health Plc. The balance owing at the yearend was £NIL.

 

During the year Optibiotix Limited transactions with Probiotix Limited were as follows:-

 

•           £NIL (2024: £171,733) for salaries and administration costs;

•           £NIL (2024: £NIL) income received on behalf of Probiotix limited; and

•           £NIL (2024: £202,948) repayments received.

 

The balance owing at the year end of £NIL was paid after the year end.

 

During the year to 31 December 2025 the Group purchased LPLDL stock to the value of £1,017,783, (2024: £751,781) from Centro Sperimentale del Latte srl, a company in which Marco Caspani is a director. At 31 December 2025 there was a balance owing to Centro Sperimentale del Latte srl of £165,499.

 

 

 

Company

 

During the year £264,218 (2024: £252,663) was paid to Probiotix Denmark Aps for the services of Steen Andersen as CEO of Probiotix Health Plc. The year-end balance was NIL.

 

During the year £851,794 (2024: £524,578) was paid to Probiotix Denmark Aps for management fees and operating costs.

 

During the year Probiotix Limited paid ProBiotix Health plc £532,500 (2024: £277,500 for management fees and operating costs.

 

Director remuneration has been fully disclosed as per requirements under note 4

 

19. Ultimate Controlling Party

 

      The Board consider that there is no overall controlling party.

 

20. Share Based payment Transactions 

 

(i)   Share options

            The Company had introduced a share option programme to grant share options as an incentive for employees.

 

Each share option converts into one ordinary share of the Company on exercise.  No amounts are paid or payable by the recipient on receipt of the option and the Company has no legal obligation to repurchase or settle the options in cash. The options carry neither rights to dividends nor voting rights prior to the date on which the options are exercised. Options may be exercised at any time from the date of vesting to the date of expiry.

 

The remaining life of all options is 8.06 years (2024: 7.25)

 

Movements in the number of share options outstanding and their related weighted average exercise prices are as follows:

 


   Number of options 

   Average exercise price


2025

2024

2025

2024


No.

No.

£

£

Outstanding at the beginning of the period

5,500,000

6,500,000

0.21

0.21

-     Granted during the period


-


-

-     Forfeited/cancelled during the year

9,250,000

(1,000,000)

0.085

-

-     Exercised during the period


-


-


───────

───────

───────

───────

Outstanding at the end of the period

14,750,000

5,500,000

0.13

0.21

 

───────

───────

───────

───────

           

Expected volatility is based on a best estimate for an AQSE listed entity. The expected life used in the model has been adjusted, based on management's best estimate, for the effects of non-transferability, exercise restrictions and behavioural considerations.

 

            Vesting conditions are as follows:

 

·    5,000,000 options vest as to 50% on a doubling of the share price to £0.42 and 50% on an annual turnover of £2.5m;

·    500,000 options, 1/3 of which vest on each of the 2-4 anniversaries of the date of grant; and

·    9,250,000 options vest as to 50% on an annual turnover of £2.5m and 50% on an annual turnover of £5m

 

20.  Share Based payment Transactions (Continued)

 

 

The fair value of awards subject to marketbased performance conditions has been measured using a Monte Carlo simulation model. The model incorporates expected volatility, the riskfree interest rate, correlation with comparator companies, and other assumptions. The fair value is determined at grant date and is not subsequently remeasured.

 

   The £2.5m turnover market based condition was achieved in the year to 31 December 2025.

 

The options issued based on anniversary dates were derived using the Black Scholes model. The following assumptions were used in the calculations:

      

Grant date

31/03/2022

Exercise price

21p

Share price at grant date

22p

Risk-free rate

1.109%

Volatility

55%

Expected life

10 years

Fair value

14.2p

 

 

A total charge of £753k (2024: £18k) has been recognised during the year for the share based payments over the vesting period.

 

7,353,333 options were exercisable at 31 December 2025. (2024:166,667)

 

(i)   Warrants

 

On 31 March 2022, the Company executed a warrant instrument to create and issue warrants to Peterhouse to subscribe for, an aggregate, of 112,857 Ordinary Shares. The warrants will be exercisable at any time from Admission for a period of ten years from Admission at the Fundraising Price.

 

Movements in the number of share warrants outstanding and their related weighted average exercise prices are as follows:

 


   Number of warrants 

Average exercise price


2025

2024

2025

2024


No.

No.

£

£

Outstanding at the beginning of the period

112,857

112.857

0.21

0.21

-    





-     Granted during the period

-

-


-

-    






───────

───────

───────

───────

Outstanding at the end of the period

112,857

112,857

0.21

0.21

 

 

───────

───────

───────

───────

 

A charge of £7,900 (2024: £7,900) has been recognised during the year for the share based payments over the vesting period.

 

The warrants were issued to the company's broker in respect of shares issues on IPO and so the fair value has been deducted from share premium.

 

21. Financial Risk Management Objectives and Policies

The Group's financial instruments comprise cash balances and receivables and payables that arise directly from its operations.

      The main risks the Group faces are liquidity risk and capital risk.

      The Board regularly reviews and agrees policies for managing each of these risks. The Group's policies for managing these risks are summarised below and have been applied throughout the period. The numerical disclosures exclude short-term debtors and their carrying amount is considered to be a reasonable approximation of their fair value.

      Interest risk

      The Group is not exposed to significant interest rate risk as it has limited interest bearing liabilities at the year end.

      Credit risk

      Management have regard to credit exposures when entering into new contracts and seek to agree settlement terms on all contracts. Credit exposure is regularly monitored by management and any overdue debts are followed up as part of the group's credit control procedures.

      Where a debt becomes significantly overdue, management have regard to credit loss provisions to reflect the existence of expected credit losses, taking account of forward looking information as well as the pattern of cash collections for that category of customer.

Liquidity risk

      Liquidity risk is the risk that Group will encounter difficulty in meeting these obligations associated with financial liabilities.

The responsibility for liquidity risks management rest with the Board of Directors, which has established appropriate liquidity risk management framework for the management of the Group's short term and long-term funding risks management requirements.

      During the period under review, the Group has not utilised any borrowing facilities.

      The Group manages liquidity risks by maintaining adequate reserves and reserve borrowing facilities by continuously monitoring forecast and actual cash flows, and by matching the maturity profiles of financial assets and liabilities.

Capital risk

The Group's objectives when managing capital are to safeguard the ability to continue as a going concern in order to provide returns for shareholders and benefits to other stakeholders and to maintain an optimal capital structure to reduce the cost of capital.

 

22. Post Balance Sheet Events

 

There were no events after the balance sheet date.

 

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