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Xenova Group PLC (XEN)

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Wednesday 12 December, 2001

Xenova Group PLC

Holding in Company

Xenova Group PLC
12 December 2001

Letter to Xenova Group PLC - dated 11 December 2001

Section 198 Companies Act

In accordance with S198 of The Companies Act we hereby notify you that RAB 
Capital Ltd, acting as investment manager for a number of commingled funds, 
yesterday disposed of 100,000 ordinary shares in Xenova Group plc. RAB Capital 
Ltd's notifiable interest is thereby reduced to 4,849,552 shares representing 
3.49% of the issued share capital.

RAB Capital does not act as custodian for its clients and therefore the shares 
are held in the nominee name of the custodian of our clients, which is Morstan 
Nominees Ltd.
From RAB Capital Limited

Letter to Xenova Group PLC - dated 11 December 2001

Companies Act 1985 (as amended):
Disclosure of Interests in Shares

In accordance with Part VI of the Companies Act 1985 (as amended) (the 'Act'), 
we write to inform you that those companies identified below no longer have a 
notifiable interest in the issued share capital of your company:

M&G Group Limited
M&G Investment Management Limited
M&G Limited

Notwithstanding the above, certain companies within the Prudential plc group of 
companies continue to have notifiable interests, details of which are set out in
the schedule below.

for and on behalf of Prudential plc

Notifiable Position Report for XENOVA GROUP ORD GBP0.10
as at 10 December 2001

Percentage holdings are calculated using an issued share capital of 139,190,000 
ORD GBP0.10 shares

                 Registered Holder         Holder        %   

Prudential plc                            8,827,246      6.34         Total     
                 PRUCLT HSBC GIS NOM(UK)                             Notifiable
                  PAC AC                  7,304,285                  Interest   
                 PRUCLT HSBC GIS NOM (UK)
                  PPL AC                  1,522,961

The Prudential Assurance Company Limited  8,827,246      6.34                   
                 PRUCLT HSBC GIS NOM(UK)                             
                  PAC AC                  7,304,285                             
                 PRUCLT HSBC GIS NOM (UK)
                  PPL AC                  1,522,961