Investor presentations

RNS Number : 4608K

Shield Therapeutics PLC

29 August 2019

 

Shield Therapeutics plc

("Shield" or the "Group")

Investor presentations

Hardman/London South East Life Sciences and Proactive One2One Investor Forum

London, UK, 29 August 2019: Shield Therapeutics plc (LSE: STX), a commercial stage, pharmaceutical company with a focus on addressing iron deficiency, announces that the Company will be presenting at the following investor forums, providing an opportunity for investors to hear about the progress being made by the Company.

Hardman/LSE Life Sciences Forum

Tim Watts, CFO, will present at the Hardman/London South East Life Sciences forum which will take place on Wednesday 11 September 2019 at the Brewers Hall, London, EC2V 7HR. Doors will open at 17.30 for an 18.15 start. A webcast of the evening will be available 24 hours after the presentation.

To register for the event and obtain further details, please contact Grace Merrall at Hardman & Co on [e-mail] 

Proactive One2One Investor Forum

Carl Sterritt, CEO, will present at the Proactive One2One Investor forum which will take place on Thursday 10 October 2019 at the Chesterfield Mayfair Hotel, 35 Charles Street, Mayfair, W1J 5EB. The evening will consist of four presentations from 6.00pm and 8.00pm.

If you would like to register, please contact Walbrook PR on 020 7933 8780 or email [e-mail].

No new material information will be disclosed at these events and the presentations will be made available on the Company's website here: https://www.shieldtherapeutics.com/presentations/

For further information please contact:

Shield Therapeutics plc	www.shieldtherapeutics.com
Carl Sterritt, Chief Executive Officer	[phone]
Tim Watts, Chief Financial Officer
Nominated Advisor and Broker
Peel Hunt LLP
James Steel/Dr Christopher Golden	[phone]
Joint Broker finnCap Ltd      Geoff Nash/Matt Radley/Alice Lane	[phone]
Financial PR & IR Advisor
Walbrook PR	[phone] or [e-mail]
Paul McManus / Lianne Cawthorne	[phone] / [phone]

About Shield Therapeutics plc

Shield is a de-risked, commercial stage, specialty pharmaceutical company delivering innovative pharmaceuticals to address patients' unmet medical needs.  The Company's clear purpose is to help its patients become people again, by enabling them to enjoy the things that make the difference in their everyday lives.  The Group has a marketed product, Feraccru® / Accrufer®, for the treatment of iron deficiency in adults which has exclusive IP rights until the mid-2030s.  Feraccru® / Accrufer®, is approved by the FDA, EMA and Swiss Medic for the treatment of iron deficiency in adults and is commercialised in the European Union by Norgine BV, with a US commercialisation partner currently being selected.  For more information please visit www.shieldtherapeutics.com.

About Feraccru®/ Accrufer®

Feraccru®/ Accrufer® is a novel, stable, non-salt based oral treatment for adults with iron deficiency with or that has been shown to be an efficacious and well-tolerated therapy in a range of controlled phase 3 trials. Following the recently announced positive results of the Phase IIIb AEGIS-H2H study in which Feraccru® demonstrated it was non-inferior to intravenously-administered Ferinject® at delivering improvements in haemoglobin levels without requiring hospital-based administration, Feraccru®/ Accrufer® offers a compelling alternative to IV Iron for those patients that cannot tolerate salt-based oral iron therapies and wish to avoid the complexities of infusion-based therapies. 

When salt-based oral iron therapies are ingested they can cause a range of mild-to-severe gastrointestinal tract (GI) adverse events, including nausea, bloating and constipation. These lead to poor tolerability, reduced patient compliance and ultimately treatment failure.  Feraccru®/ Accrufer® is not an iron salt; iron can be absorbed from the ferric maltol molecule and, as a result, it does not routinely cause the same treatment-limiting intolerance issues.  

Prior to Feraccru®/ Accrufer®, IV iron therapies were the only realistic alternative treatment option for patients intolerant of or unwilling to take salt-based oral iron therapies.  However, use of such an invasive, costly, inconvenient and complex to administer treatment option, which is associated with potentially life-threatening and spontaneous hypersensitivity reactions, means there remains a clear unmet medical need for patients with iron deficiency to have access to an effective therapy like Feraccru®/ Accrufer® that is well tolerated, convenient and does not require hospital-based administration.

About Iron Deficiency

The WHO state that iron deficiency is the most common and widespread nutritional disorder in the world.  As well as affecting a large number of children and women in non-industrialized countries, it is the only nutrient deficiency which is also significantly prevalent in virtually all industrialized nations. There are no current global figures for iron deficiency, but using anaemia as an indirect indicator it can be estimated that most preschool children and pregnant women in non-industrialized countries, and at least 30-40% in industrialized countries, are iron deficient.

 

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