Holding(s) in Company

Prodesse Investment Limited
21 March 2007



TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):
Prodesse Investment Limited

2. Reason for the notification (please state Yes/No): ( )

An acquisition or disposal of voting rights: (N)

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: (N)

An event changing the breakdown of voting rights: (N)

Other (please specify) : (N/A see additional notes)

3. Full name of person(s) subject to the notification obligation (iii):
Legal & General Investment Management Limited (LGIM)
Legal & General Group Plc (Group)

4. Full name of shareholder(s) (if different from 3.) (iv):
N/A

5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):
N/A

6. Date on which issuer notified:
20 March 2007

7. Threshold(s) that is/are crossed or reached:
Below 5% (Group)
Below 5% (LGIM)

8. Notified details:

A: Voting rights attached to shares

Class/type of shares if  Situation previous to the Triggering transaction (vi)
possible using the ISIN
CODE
GB00B06FN106             Number of shares           Number of voting Rights
                                                    (viii)
Ordinary USD             841,168                    3.03%
0.01                     (under S-198 on 05/04/
                         2006)

Resulting situation after the triggering transaction (vii)

Class/type of    Number of       Number of voting rights  % of voting rights
shares if        shares          (ix)
possible using
the ISIN CODE
                 Direct          Direct    Indirect (xi)  Direct    Indirect
                                 (x)
                      Below 5% (see additional information)

B: Financial Instruments
Resulting situation after the triggering transaction (xii)

Type of      Expiration Exercise/      Number of voting rights that may % of
financial    Date       Conversion     be acquired if the instrument is voting
instrument   (xiii)     Period/ Date   exercised/ converted.            rights
                        (xiv)


Total (A+B)
Number of voting rights                      % of voting rights
                    Below 5% (see additional information)

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):

Legal & General Group Plc (Direct and Indirect) (Below 5%)

Legal & General Investment Management (Holdings) Limited (LGIMH)
(Direct and Indirect) (Below 5%)

Legal & General Investment Management Ltd (Indirect) (LGIM) (Below 5%)

                   Legal & General Group Plc (Direct) (L&G)

Legal & General Investment Management         Legal & General Insurance
Holdings Limited (Direct) (LGIMHD)            Holdings Limited (Direct) (LGIH)

Legal & General Assurance (Pensions           Legal & General Assurance
Management) Limited (PMC)                     Society Limited (LGAS & LGPL)

                                              Legal & General Pensions 
                                              Limited (Direct) (LGPL)

Proxy Voting:

10. Name of the proxy holder:
N/A

11. Number of voting rights proxy holder will cease to hold:
N/A

12. Date on which proxy holder will cease to hold voting rights:
N/A

13. Additional information:
Notification using the total voting rights figure of 25,625,550.

First notification under DRT Sourcebook.

As Prodesse Investment Limited is a non-EEA Issuer the threshold for
notifications is 5%. Our last disclosure was made under Section 198 of the
Companies Act 1985 when the threshold was 3%, therefore we do not currently 
have a notifiable holding.

14. Contact name:
Helen Lewis

15. Contact telephone number:
020 7528 6742





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