Holding(s) in Company

Prodesse Investment Limited 15 March 2006 Prodesse Investment Limited ('Prodesse') 15 March 2006 Notification of Shareholdings Based upon letters received from shareholders and information provided by the Company's registrar, as at 7 March 2006 the Directors of Prodesse believe that the following list comprised all holders of 3% or more of the issued Ordinary Shares of the Company. Number of Percentage (%) Ordinary Shares --------------------------------- ---------------- ---------- CSFB Prime Brokerage 3,321,183 11.97 Lehman Brothers 2,823,094 10.17 Deutsche Prime Brokerage 2,650,000 9.55 Citigroup Global Markets UK Equity Ltd 1,468,000 5.29 Henderson Global Investors 1,240,000 4.47 Artemis Investment Management 1,200,000 4.32 Credit Suisse Equities 1,000,000 3.60 UBS Global Asset Management 1,000,000 3.60 Threadneedle Collateral (SL) 932,500 3.36 Enquiries: RBSI Fund Services (Guernsey) Limited: Sara Radford/Paul Smith 01481 743004 Merrill Lynch: Peter Tracey 020 7996 4541 Will Smith 020 7996 2490 This information is provided by RNS The company news service from the London Stock Exchange
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