Holding(s) in Company

Prodesse Investment Limited
15 April 2008


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached :

Prodesse Investment Limited

2. Reason for the notification (please state Yes/No): ( )

An acquisition or disposal of voting rights: ( Yes )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: ( No )

An event changing the breakdown of voting rights: ( No )

Other (please specify) : ( No )

3. Full name of person(s) subject to the notification obligation (iii):

Ruffer LLP

4. Full name of shareholder(s) (if different from 3.) (iv):

5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

11 April 2008

6. Date on which issuer notified:

14 April 2008

7. Threshold(s) that is/are crossed or reached:

8%

8. Notified details:

A: Voting rights attached to shares

Class/type of shares if  Situation previous to the Triggering transaction (vi)
possible using the ISIN
CODE
                         Number of shares    Number of voting Rights (viii)

GB00B06FN106             59,318              59,318





Resulting situation after the triggering transaction (vii)

Class/type of shares if     Number of   Number of voting     % of voting
possible using the ISIN     shares      rights (ix)          rights
CODE
                            Direct      Direct (x)  Indirect Direct   Indirect
                                                    (xi)
                            2,640,818   2,640,818            8.52%

B: Financial Instruments
Resulting situation after the triggering transaction (xii)

Type of      Expiration Exercise/      Number of voting rights that may % of
financial    Date       Conversion     be acquired if the instrument is voting
instrument   (xiii)     Period/ Date   exercised/ converted.            rights
                        (xiv)

Total (A+B)
Number of voting rights                      % of voting rights

2,640,818                                    8.52%

9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):

Proxy Voting:

10. Name of the proxy holder:
.................

11. Number of voting rights proxy holder will cease to hold:
.................

12. Date on which proxy holder will cease to hold voting rights:
.................

13. Additional information:
.................

14. Contact name:

Louise Ellis

15. Contact telephone number:

020 7963 8146




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