Director/PDMR Shareholding

Oxford Biomedica PLC
23 March 2006


                      Oxford BioMedica plc ('the Company')
                                        
                            Interest in share options

Oxford BioMedica (OXB:L). The Company today announced that, as part of a grant
of share options to a number of eligible employees, it had granted 172,531
options over 1p ordinary shares under the Oxford BioMedica 1996 (No.1) share
option scheme on 21 March 2006 to Sharon Wood, who is an employee of Oxford
BioMedica and is the wife of Andrew Wood, Chief Financial Officer and Company
Secretary.

It is the Company's policy to award share options to all UK employees, following
the announcement of full-year or half-year results. The exercise price for the
options is 29.0 pence per share. The options become exercisable three years from
the date of grant and remain exercisable up to seven years from the date of
grant. Sharon Wood's total interest in options over the Company's shares is
172,531.


Andrew Wood
Company Secretary, Oxford BioMedica plc
23 March 2006



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