Holding(s) in Company

Intl. Biotechnology Trust PLC
28 November 2005




                                                                22 November 2005


                     Beneficial Share Interest Notification


The Company was notified on 22 November 2005 that as at 9 November 2005, QVT
Fund LP held a beneficial interest, through CrestCo Limited, in 7,217,000
ordinary shares of 25p each in the Company, being 15.17% of the 47,565,467
shares in issue.



Enquiries:

John Spedding

Schroder Investment Management Limited            Tel: [phone]





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