Director Shareholding

GlaxoSmithKline PLC
08 April 2005


                              Directors Interests


I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned Director arising from the
purchase of Ordinary Shares at a price of £12.40 per Ordinary Share on 07 April
2005 through the Company's ShareReward Plan ("the Plan") which Mr Heslop entered
on 5 October 2001:
                         
Mr J S Heslop            Acquisition of 7 Ordinary Shares under the Dividend 
                         Reinvestment element of the Plan


Mr Heslop and the Company were advised of this information on 08 April 2005.


S M Bicknell
Company Secretary

08 April 2005


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