Director Shareholding

GlaxoSmithKline PLC
15 March 2004



                              Directors' Interests

The Administrators of the GlaxoSmithKline US Retirement Savings Plan notified
GlaxoSmithKline plc and the under-mentioned Directors on 15 March 2004 of an
increase in their interests in Ordinary Share ADRs on 12 March 2004 at a price
of $40.00 per share:-




Dr J P Garnier                                                           6
Dr T Yamada                                                              108



S M Bicknell

Company Secretary

15 March 2004


                      This information is provided by RNS
            The company news service from the London Stock Exchange