Director Shareholding

GlaxoSmithKline PLC
01 October 2003

                              Directors' Interests

I give below details of changes in the directors' interests in the Ordinary
Shares and American Depository Shares (ADSs) of GlaxoSmithKline plc.

On 1 October 2003, the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the automatic share allocation arrangements for non-executive Directors
for the period of service from 1 July to 30 September 2003, as listed below.

Non Executive Director                Ordinary Shares        American Depository
                                                                Shares (ADS)
Sir Christopher Hogg                       1,500          
Dr Michele Barzach                          250
Mr Lawrence Culp                                                    125
Mr Crispin Davis                            250
Sir Peter Job                               250
John McArthur                                                       125
Donald McHenry                                                      125
Sir Ian Prosser                             250
Dr Ronaldo Schmitz                          250
Dr Lucy Shapiro                                                     125

At the same time the following non-executive Directors were provisionally
allocated the following awards over Ordinary Shares and ADSs in the Company
under the share election element of the share allocation arrangements for
non-executive Directors for the period of service from 1 July to 30 September
2003, as listed below.

Non Executive Director                Ordinary Shares        American Depositary
                                                                   Shares

                                                                    (ADS)
Sir Christopher Hogg                     2969.1211
Mr Lawrence Culp                                                  421.1511
Mr Crispin Davis                          890.7363
Sir Peter Job                             890.7363
Sir Ian Prosser                           544.3389
Dr Ronaldo Schmitz                        435.4711

The Company and the directors were informed of these allocations on 1 October
2003.


S M Bicknell
Company Secretary
1 October 2003


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