Director Shareholding

GlaxoSmithKline PLC
26 January 2004


                              Directors' Interests


I give below details of changes in directors' interests in the Ordinary Shares
of GlaxoSmithKline plc.

                         
23 January 2004          The Administrators of the SmithKline Beecham Employee 
                         Benefit Trust ("the Trust") notified the Company on 26 
                         January 2004 that 2,012 Ordinary shares had been 
                         transferred from the Trust to participants in the 
                         SmithKline Beecham Bonus Investment Plan.

                         The Trust also notified the Company on 26 January 2004 
                         that 351 Ordinary shares had transferred from the Trust 
                         to participants in the GlaxoSmithKline Annual 
                         Investment Plan.

The Trust is a discretionary fund of which all non US employees or former
employees of GlaxoSmithKline plc and its subsidiaries are potential
beneficiaries. One of the Company's directors, John Coombe is therefore
interested in the shares held in the fund from time to time in the same way as
other non US employees or former employees of GlaxoSmithKline plc and its
subsidiaries.


S M Bicknell

Company Secretary

26 January 2004


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