Director Shareholding

GlaxoSmithKline PLC 06 January 2003 Directors' Interests I give below details of changes in directors' interests in the Ordinary Shares of GlaxoSmithKline plc. 3 January 2003 The Administrators of the GlaxoSmithKline US Retirement Savings Plan ("the Plan") notified GlaxoSmithKline plc on 6 January 2003, that as a result of movement in the fund on the 3 January 2003, the number of Ordinary Share ADRs held by the fund had increased from 18,290,955 to 18,320,180 at an average price of $38.83. The Plan is a discretionary fund of which all employees or former employees of GlaxoSmithKline plc and its subsidiaries are potential beneficiaries. Two of the Company's directors, Dr J P Garnier and Mr J D Coombe are therefore interested in the shares held in the fund from time to time in the same way as other employees or former employees of GlaxoSmithKline plc and its subsidiaries. S M Bicknell Company Secretary 6 January 2003 This information is provided by RNS The company news service from the London Stock Exchange

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