Director Shareholding

GlaxoSmithKline PLC
22 July 2002


                              Directors' Interests

I give below details of a change in the interests in Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned Director arising from the
purchase of Ordinary Shares at a price of £13.48 per Ordinary Share on 9 July
2002 through the Company's ShareReward Plan ("the Plan") which Mr Coombe entered
on 5 October 2001:


Mr J D Coombe                      Acquisition of 9 Ordinary Shares under the partnership element of the
                                   Plan (personal contribution)

                                   Acquisition of 9 Ordinary Shares under the matching element of the Plan
                                   (Company contribution)



Mr Coombe and the Company were advised of this information on 22 July 2002.


S M Bicknell

Company Secretary

22 July 2002





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