Director Shareholding

GlaxoSmithKline PLC
12 October 2001

                             Director's Interests

I give below details of changes in interests in the Ordinary Share ADRs of
GlaxoSmithKline plc (each ADR represents two Ordinary Shares) in respect of
the under-mentioned director arising from the purchase of Ordinary Share ADRs
on 4 October 2001 from the reinvestment of the dividend paid to Ordinary Share
ADR holders on the 4 October 2001 through the US Global BuyDirect Plan
administered by The Bank of New York:-

Mr D F     Beneficial interest in 0.1973 Ordinary Share ADRs purchased at a
McHenry    price of $56.9135 per ADR.

SM Bicknell

Company Secretary

12 October 2001