Director Shareholding

GlaxoSmithKline PLC
6 July 2001



                             Directors' Interests



I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the undermentioned directors:

Sir Richard Beneficial interest in 26 Ordinary Shares purchased under a
Sykes       Personal Equity Plan on 2 July 2001 at £19.74.

            Lady Janet Sykes (wife); beneficial interest in 16 Ordinary shares
            purchased under a Personal Equity Plan on 2 July 2001 at £19.74.

Mr J D      Beneficial interest in 15 Ordinary Shares purchased under a
Coombe      Personal Equity Plan on 2 July 2001 at £19.74.

            Mrs G A Coombe (wife); beneficial interest in 11 Ordinary Shares
            purchased under a Personal Equity Plan on 2 July 2001 at £19.74.

Sir Peter   Beneficial interest in 2 Ordinary Shares purchased under a Personal
Job         Equity Plan on 2 July 2001 at £19.74.

Sir         Beneficial interest in 2 Ordinary Shares purchased under a Personal
Christopher Equity Plan on 2 April 2001 at £18.17; and
Hogg
            Beneficial interest in 17 Ordinary Shares purchased under a
            Personal Equity Plan on 2 July 2001 at £19.74.


The Directors and the Company were advised of these transactions on 5 July
2001.


S M Bicknell
Company Secretary

6 July 2001