Director/PDMR Shareholding

GlaxoSmithKline PLC
02 August 2005


   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


I give below details of changes in interests in the Ordinary Shares of
GlaxoSmithKline plc in respect of the under-mentioned Director:-
                    
Dr L Shapiro        The Administrators of the GlaxoSmithKline Scientific 
                    Advisory Board Share Allocation Plan notified 
                    GlaxoSmithKline plc on 02 August 2005 that 307 American
                    Depository Shares (ADS) had been purchased for Dr Shapiro at 
                    a price of $47.77 on 29 July 2005 as per the share election 
                    arrangements for the Scientific Advisory Board. Dr Shapiro 
                    was also notified of this change on 02 August 2005.

This notification relates to a transaction notified in accordance with
Disclosure rule 3.1.4R(1)(b).


S M Bicknell
Company Secretary
02 August 2005


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