Director/PDMR Shareholding

GlaxoSmithKline PLC
17 March 2006




   Notification of Transactions of Directors, Persons Discharging Managerial
                      Responsibility or Connected Persons


The Administrators of the GlaxoSmithKline Annual Investment Plan notified the
Company and the under mentioned person on 17 March 2006 of an increase in his
interest in Ordinary Shares ADRs  at a price of $54.65 per share:-


Dr D Pulman                                       2,112.946


This notification relates to a transaction notified in accordance with
Disclosure Rule 3.1.4R(1)(a).


S M Bicknell
Company Secretary

17 March 2006


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