Rule 8.1- (Sygen)

Genus PLC
11 November 2005


FORM 8.1

DEALINGS BY OFFERORS, OFFEREE COMPANIES OR THEIR ASSOCIATES
FOR THEMSELVES OR FOR DISCRETIONARY CLIENTS
(Rules 8.1(a) and (b)(i) of the City Code on Takeovers and Mergers)

1. KEY INFORMATION

Name of person dealing (Note 1)                          Genus plc
Company dealt in                                         Sygen International
                                                         plc
Class of relevant security to which the dealings being   Ordinary Shares of 10
disclosed relate (Note 2)                                pence each

Date of dealing                                          11 November 2005



2. INTERESTS, SHORT POSITIONS AND RIGHTS TO SUBSCRIBE

(a) Interests and short positions (following dealing) in the class of relevant
security dealt in (Note 3)

                                                     Long             Short
                                             Number  (%)           Number (%)
(1) Relevant
securities                               31,155,606 10.55
(2) Derivatives (other than options)
(3) Options and agreements to purchase/sell
                                      Total

(b) Interests and short positions in relevant securities of the company, other
than the class dealt in (Note 3)

Class of relevant security:                           Long          Short
                                                  Number (%)     Number (%)
(1) Relevant securities
(2) Derivatives (other than options)
(3) Options and agreements to purchase/sell
                                      Total

(c) Rights to subscribe (Note 3)

Class of relevant security:                                  Details



3. DEALINGS (Note 4)

(a) Purchases and sales

Purchase/sale     Number of securities          Price per unit (Note 5)
Purchase                 1,502,421                     62.375p

(b) Derivatives transactions (other than options)

Product      Long/short (Note   Number of securities (Note Price per unit (Note
name,        6)                 7)                         5)
e.g. CFD



(c) Options transactions in respect of existing securities
(i) Writing, selling, purchasing or varying

Product  Writing,     Number of         Exercise   Type, e.g. Expiry   Option
name,    selling,     securities to                American,           money
         purchasing,  which the option             European
         varying      relates (Note 7)             etc.
         etc.
e.g.                                    price                 date     paid/
call                                                                   received
option                                                                 per unit
                                                                       (Note 5)



(ii) Exercising

Product name, e.g. call      Number of            Exercise price per unit (Note
option                       securities           5)


(d) Other dealings (including new securities) (Note 4)

Nature of transaction (Note 8) Details   Price per unit (if applicable) (Note 5)



4. OTHER INFORMATION

Agreements, arrangements or understandings relating to options or derivatives

Full details of any agreement, arrangement or understanding between the person
disclosing and any other person relating to the voting rights of any relevant
securities under any option referred to on this form or relating to the voting
rights or future acquisition or disposal of any relevant securities to which any
derivative referred to on this form is referenced. If none, this should be
stated.


Is a Supplemental Form 8 attached? (Note 9) YES/NO

Date of disclosure                                       11 November 2005

Contact name                                             Tristan van der
                                                         Vijver
Telephone number                                         020 7614 8398

Name of offeree/offeror with which associated            Genus Plc
Specify category and nature of associate status (Note    Offeror
10)


Notes

The Notes on Form 8.1 can be viewed on the Takeover Panel's website at
www.thetakeoverpanel.org.uk




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