Rule 8.1- (Sygen)

Genus PLC 01 November 2005 FORM 8.1 DEALINGS BY OFFERORS, OFFEREE COMPANIES OR THEIR ASSOCIATES FOR THEMSELVES OR FOR DISCRETIONARY CLIENTS (Rules 8.1(a) and (b)(i) of The City Code on Takeovers and Mergers) Name of purchaser/vendor * Genus plc Company dealt in Sygen International plc Relevant security dealt in Ordinary shares of 10 pence each Name of offeree / offeror with which Genus plc associated Specify category and nature of associate status Offeror # Date of dealing 1 November 2005 DEALINGS + Amount bought Price per unit (currency must be stated) 6,000,000 62.1667 pence Amount sold Price per unit (currency must be stated) N/A N/A Resultant total amount and percentage of the same relevant security owned or controlled 6,000,000 (2.03%) IS A SUPPLEMENTAL FORM 8 (DERIVATIVE)/FORM 8 (OPTION) ATTACHED? NO Date of disclosure 1 November 2005 Contact name Tom Forcier Telephone number 020 7614 8399 * Specify the owner or controller in addition to the person dealing. The naming of nominees or vehicle companies is insufficient. In the case of disclosure of dealings by fund managers on behalf of discretionary clients, the clients need not be named. # See the definition of 'associate' in the Definitions Section of the Code. + If disclosing dealings/holdings in derivatives or options, please attach Supplemental Form 8 (Derivative) or Supplemental Form 8 (Option), as appropriate. For details of the Code's dealing disclosure requirements, see Rule 8 and its Notes which can be viewed on the Takeover Panel's website at www.thetakeoverpanel.org.uk. This information is provided by RNS The company news service from the London Stock Exchange

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