Trading Update

Deltex Medical Group PLC 12 January 2006 Deltex Medical Group plc Pre-close update on the year ended 31 December 2005 12 January 2006 Deltex Medical Group plc ('Deltex Medical' or the 'Company'), the AIM listed haemodynamic monitoring company, today announces an update on progress in the year ended 31 December 2005. During 2005 the Company made significant progress towards its goal of establishing the use of its CardioQTM system as a standard of care in the monitoring and management of patients undergoing major surgery. As a result, the directors anticipate that sales for the year will be in excess of £3.0 million which is within the range of market expectations. In the UK, the number of doctors wanting to use Deltex Medical's technology continued to grow rapidly as did the number of clinical settings in which the CardioQ system has been shown to be both cost effective and clinically beneficial to the patients doctors are treating. Sales continued to grow steadily in the UK, although at a far slower rate than clinical demand due mostly to the very difficult financial management challenges facing many NHS hospitals. Over 80% of the growth in UK sales came from probe sales and maintenance cover. In the middle of the year, and somewhat later than originally anticipated, the Improving Surgical Outcomes Group (ISOG) published a pamphlet outlining a range of proposals for improving surgical patient care in the UK that have at their heart the routine use of haemodynamic optimisation to reduce complications and hospital stay. ISOG, an independent group of leading anaesthetists, intensivists and surgeons, enjoys widespread support and is working with policy makers, health service managers and industry to achieve its aims. The Company has been working closely with a group of surgeons in northern Europe and the UK who are leading the world in improving the quality of large bowel surgery, primarily in cancer patients, through the Enhanced Recovery After Surgery (ERAS) project. A number of surgeons that follow the ERAS approach have asked that their patients be treated using the CardioQ following presentation of excellent results in these patients by surgeons from the Freeman Hospital in Newcastle. It is hoped that haemodynamic optimisation will become established as a standard element of the ERAS approach in the future. In the US, sales of CardioQ monitors were significantly ahead of prior years and included the purchase of four units by the William Beaumont Army Hospital in El Paso, Texas for use in the intensive care unit and in patients undergoing elective or emergency surgery in the operating room. These sales and the increasing awareness of the need for better, earlier and safer haemodynamic monitoring in the US perhaps represent the first signs of real growth in this market. In Europe, the Company has been working with a leading French doctor to develop the protocol for the first multi-centred, randomised clinical trial into the effects of haemodynamic optimisation, using the CardioQ, in patients undergoing surgery for repair of a fractured hip. This clinical trial, which has been approved by the French authorities, will be the first to treat sufficient patients to show an impact on death rates. Patient enrolment is scheduled to start in the second quarter of 2006. The sale of three of the Company's wholly non-invasive monitor, the SupraQTM, to the Medway Hospital in Gillingham marks the successful completion of the first phase of this research and development project. The Company will be working closely with doctors at the Medway Hospital to undertake further clinical research using these devices and as part of the second phase of development work that will lead to a second-generation system for mass-market use. Actual cash consumption in the second half of the year was, as expected, significantly lower than at any time in the Company's history. The Directors believe that the Company has sufficient cash resources to see it through to profitability. Nigel Keen, Deltex Medical's Chairman, commented: 'Early in 2005 we configured the Company to ensure that we would have sufficient cash resources available to reach profitability, irrespective of the ability of doctors in our home market to secure the funding they need to purchase our products. Given the situation facing the UK NHS, that decision has proved to be prudent. Nevertheless, we have seen good progress this year, with those doctors that have ready access to CardioQs using them on more and more patients as user confidence and experience grows. 'There are early and encouraging signs real progress in a number of European countries where we have not long had a presence and in the US market too. I look forward to seeing further progress towards our goals in 2006.' For further information, please contact:- Deltex Medical Group plc 01243 774 837 Nigel Keen, Chairman nigel.keen@deltexmedical.com Andy Hill, Chief Executive andy.hill@deltexmedical.com Ewan Phillips, Finance Director ewan.phillips@deltexmedical.com Financial Dynamics 0207 831 3113 David Yates david.Yates@fd.com John Gilbert john.gilbert@fd.com Notes for Editors Deltex Medical manufactures and markets the CardioQ monitor, which uses disposable ultra-sound probes inserted into the oesophagus to determine the amount of blood being pumped around the body - 'circulating blood volume'. Reduced circulating blood volume is known as hypovolaemia, which leads to insufficient oxygen being delivered to the organs. This causes medical complications including peripheral and major organ failure which can lead to death. Hypovolaemia, which is akin to severe dehydration, affects virtually every patient having surgery because of the combined effects of pre-operative starvation, the impact of the anaesthetic agents and trauma from the surgery itself. Using fluids and drugs, guided by the CardioQ, to optimise the amount of circulating blood significantly reduces post-operative complications allowing patients to make a faster, more complete recovery and return home earlier. The CardioQ incorporates the Company's proprietary software and a small diameter, easy-to-use, minimally invasive, disposable oesophageal probe that is used for transmitting and receiving an ultra-sound signal. By using this technology, the CardioQ provides clinicians with the ability to haemodynamically optimise critically ill patients and those undergoing routine moderate to major surgery through the controlled administration of fluid and drugs. Haemodynamic optimisation has been scientifically proven to improve the speed and quality of patient recovery and reduce hospital stay. There are already over 1,250 CardioQs currently in use in hospitals worldwide and distribution arrangements are in place in over 30 countries. In addition, there are currently more than 90 clinical publications on the use of the CardioQ which have repeatedly:- • validated the results of the Monitor against known standards for measuring cardiac output, demonstrating that the technology works • proved that the CardioQ works in a wide range of surgical procedures • demonstrated that the Company's technology provides significant health and economic benefits by helping to reduce post-operative complications and length of hospital stays by an average of 30 to 40 per cent for a wide range of patients. This information is provided by RNS The company news service from the London Stock Exchange
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