Transaction in Own Shares

AstraZeneca PLC
13 February 2006

                    REPURCHASE OF SHARES IN ASTRAZENECA PLC


AstraZeneca PLC announced that on 10 February 2006, it purchased for
cancellation 850,000 ordinary shares of AstraZeneca PLC at a price of 2643 pence
per share. Upon the cancellation of these shares, the number of shares in issue
will be 1,577,623,356.



G H R Musker
Company Secretary
13 February 2006


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