Holding(s) in Company

Allergy Therapeutics PLC
21 April 2005


Schedule 10

NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

Allergy Therapeutics plc

2. Name of shareholder having a major interest

Fidelity International Limited

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Non-beneficial interest

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

Nominee/registered name       Share held     Management Company

JP Morgan, Bournemouth             849,300   Fidelity Inv Services Ltd
Bank of New York, Brussels         441,562   Fidelity Pension Mgmnt (FPM)
Bankers Trust London               135,700   FPM
CITIBANK London                    128,400   FPM
Clydesdale Bank plc                 58,300   FPM
JP Morgan, Bournemouth             288,500   FPM
Mcllon Bank                        307,900   FPM
Midland Securities Services         74,300   FPM
Northern Trust London              609,300   FPM
State STR BK and TR Co London      214,598   FPM
Brown Bros Harrimn Ltd LUX         350,000   FPM

5. Number of shares / amount of stock acquired

910,860

6. Percentage of issued class

1.447%

7. Number of shares / amount of stock disposed

-

8. Percentage of issued class

-

9. Class of security

Ordinary shares

10. Date of transaction

Not notified

11. Date company informed

20th April 2005

12. Total holding following this notification

3,457,860

13. Total percentage holding of issued class following this notification

5.49%

14. Any additional information

Notifiable interest also comprises of Mr. Edward C. Johnson 3d A principle
Shareholder of Fidelity International Limited

15. Name of contact and telephone number for queries

Ian Postlethwaite - 01903 844 721

16. Name and signature of authorised company official responsible for making
this notification

Ian Potlethwaite

Date of notification

20 April 2005

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for loss of business or loss of profits) arising in contract, tort or otherwise
from the use of or inability to use this document, or any material contained in
it, or from any action or decision taken as a result of using this document or
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