Holding(s) in Company

Advanced Medical Solutions Grp PLC
28 February 2008




TR-1: Notifications of Major Interests in Shares


1. Identity of the issuer or the underlying issuer of existing
shares to which voting rights are attached:

Advanced Medical Solutions


2. Reason for notification (yes/no)
                                                                                                

An acquisition or disposal of voting rights                                Yes


An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached


An event changing the breakdown of voting rights


Other (please specify):
                                                     
3. Full name of person(s) subject to notification
obligation:

AXA S.A, 25 Avenue Matignon, 75008 Paris and its group companies


4. Full name of shareholder(s) (if different from
3):
                                                                         

5. Date of transaction (and date on which the
threshold is crossed or reached if different):

26/02/08
                                                                          

6. Date on which issuer notified:

27/02/08
                                                                            

7. Threshold(s) that is/are crossed or reached:

13%

8: Notified Details
A: Voting rights attached to shares


Class/type of       Situation previous to    Resulting situation after the triggering transaction
shares              the triggering
                    transaction
If possible use     Number of    Number of   Number of   Number of voting rights  Percentage of voting
ISIN code           shares       voting      shares                               rights
                                 rights

                                                         Direct      Indirect     Direct      Indirect

Ordinary 5p shares   18,946,661  18,946,661    451,161     415,161    18,697,057    0.29       13.07
   GB0004536594


B: Financial Instruments


Resulting situation after the triggering transaction


Type of financial    Expiration date      Exercise/ conversion No. of voting rights  Percentage of voting
instrument                                period/date          that may be acquired  rights
                                                               (if the instrument
                                                               exercised/converted)





Total (A+B)


Number of voting rights                             Percentage of voting rights


          19,112,218                                             13.36


9. Chain of controlled undertakings through which the voting rights and /or the
financial instruments are effectively held, if applicable:


Name of the Company/Fund                                  No of shares              % of issued share cap

Sun Life Pensions Mgmt Ltd                                      15,161                               0.01

Direct
Sun Life Pensions Mgmt Ltd                                     400,000                               0.28

Direct
AXA Framlington                                             10,000,000                               6.99

Framlington Innovative Growth

Indirect
AXA Framlington                                              5,100,000                               3.56

Health

Indirect
Framlington onshore private clients                          2,631,500                               1.84

Indirect
AWF Framlington Health                                         965,557                               0.67

Indirect
                                  Total Direct                 415,161                               0.29

                                Total Indirect              18,697,057                              13.07

                                         Total              19,112,218                              13.36


Proxy Voting:

10. Name of proxy holder:                                                    N/A

11. Number of voting rights proxy holder will cease                          N/A
to hold:

12. Date on which proxy holder will cease to hold                            N/A
voting rights:


13. Additional information:

14 Contact name:                                       Mary Tavener

15. Contact telephone name:                            [phone]






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