Holding(s) in Company

For filings with the FSA include the annex                                              
                                                                                        
For filings with issuer exclude the annex                                               
                                                                                        
                                                                                        
                                                                                        
TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                         
                                                                                        
                                                                                        
                                                                                        
1. Identity of the issuer or the underlying issuer                                      
of existing shares to which voting rights are                  Scancell Holdings plc    
attached:ii                                                                             
                                                                                        
2 Reason for the notification (please tick the appropriate box or boxes):               
                                                                                        
An acquisition or disposal of voting rights                                            X
                                                                                        
An acquisition or disposal of qualifying financial instruments which may result         
in the acquisition of shares already issued to which voting rights are attached         
                                                                                        
An acquisition or disposal of instruments with similar economic effect to               
qualifying financial instruments                                                        
                                                                                        
An event changing the breakdown of voting rights                                        
                                                                                        
Other (please specify):                                                                 
                                                                                        
3. Full name of person(s) subject to the                        Calculus Capital Limited
notification obligation:iii                                                             
                                                                                        
4. Full name of shareholder(s)                          HSBC Global Custody (UK) Limited
 (if different from 3.):iv                                                              
                                                                                        
5. Date of the transaction and date on                                                  
which the threshold is crossed or                                           26 July 2011
reached: v                                                                              
                                                                                        
6. Date on which issuer notified:                                           26 July 2011
                                                                                        
7. Threshold(s) that is/are crossed or                                      10,11,12,13%
reached: vi, vii                                                                        
                                                                                        


 

8. Notified details:                                                                        
                                                                                            
A: Voting rights attached to shares viii, ix                                                
                                                                                            
Class/type   Situation previous           Resulting situation after the triggering          
of           to the triggering            transaction                                       
shares       transaction                                                                    
                                                                                            
             Number           Number      Number     Number of voting    % of  voting rights
if possible  of               of          of shares  rights              x                  
using        Shares           Voting                                                        
the ISIN                      Rights      Direct     Direct xi  Indirect Direct  Indirect   
CODE                                                            xii                         
                                                                                            
Ordinary                                                                                    
Shares                                                                                      
                                                                                            
ISIN:        15,277,780       15,277,780  25,277,780 25,277,780          13.02 %            
GB00B39J5N63                                                                                
                                                                                            
                                                                                            
                                                                                            
                                                                                            
                                                                                            
B: Qualifying Financial Instruments                                                         
                                                                                            
Resulting situation after the triggering transaction                                        
                                                                                            
Type of        Expiration      Exercise/              Number of voting          % of voting 
financial      date xiii       Conversion Period xiv  rights that may be        rights      
instrument                                            acquired if the                       
                                                      instrument is                         
                                                      exercised/ converted.                 
                                                                                            
                                                                                            
                                                                                            
                                                                                            
                                                                                            
C: Financial Instruments with similar economic effect to Qualifying Financial               
Instruments xv, xvi                                                                         
                                                                                            
Resulting situation after the triggering transaction                                        
                                                                                            
Type of       Exercise price  Expiration Exercise/   Number of voting      % of voting      
financial                     date xvii  Conversion  rights instrument     rights xix, xx   
instrument                               period      refers to                              
                                         xviii                                              
                                                                                            
                                                                                            
                                                                           Nominal Delta     
                                                                                            
                                                                                            
                                                                                            
                                                                                            
                                                                                            
Total (A+B+C)                                                                               
                                                                                            
Number of voting rights                          Percentage of voting rights                
                                                                                            
25,277,780                                       13.02 %                                    
                                                                                            


 

9. Chain of controlled undertakings through which the voting rights and/or the          
financial instruments are effectively held, if applicable: xxi                          
                                                                                        
                                                                                        
                                                                                        
N/A                                                                                     
                                                                                        
                                                                                        
                                                                                        
Proxy Voting:                                                                           
                                                                                        
10. Name of the proxy holder:                                                        N/A
                                                                                        
11. Number of voting rights proxy holder will cease                                  N/A
to hold:                                                                                
                                                                                        
12. Date on which proxy holder will cease to hold                                    N/A
voting rights:                                                                          
                                                                                        
                                                                                        
                                                                                        
13. Additional information:                                                          N/A
                                                                                        
14. Contact name:                                               Calculus Capital Limited
                                                                                        
15. Contact telephone number:                                              0207 493 4940
                                                                                        


 

Note: Annex should only be submitted to the FSA not the issuer                          
                                                                                        
Annex: Notification of major interests in sharesxxii                                    
                                                                                        
                                                                                        
                                                                                        
A: Identity of the persons or legal entity subject to the notification                  
obligation                                                                              
                                                                                        
Full name                                                                               
                                                                                        
(including legal form of legal entities)                                                
                                                                                        
                                                                                        
                                                                                        
Contact address                                                                         
                                                                                        
(registered office for legal entities)                                                  
                                                                                        
                                                                                        
                                                                                        
Phone number & email                                                                    
                                                                                        
                                                                                        
                                                                                        
Other useful information                                                                
                                                                                        
(at least legal representative for legal persons)                                       
                                                                                        
                                                                                        
                                                                                        
                                                                                        
                                                                                        
B: Identity of the notifier, if applicable                                              
                                                                                        
Full name                                                                               
                                                                                        
                                                                                        
                                                                                        
Contact address                                                                         
                                                                                        
                                                                                        
                                                                                        
Phone number & email                                                                    
                                                                                        
                                                                                        
                                                                                        
Other useful information                                                                
                                                                                        
(e.g. functional relationship with the person or legal entity subject to the            
notification obligation)                                                                
                                                                                        
                                                                                        
                                                                                        
C: Additional information                                                               
                                                                                        
                                                                                        
                                                                                        
For notes on how to complete form TR-1 please see the FSA website.