Re Contract

PRESS RELEASE PROTEOSHOP COLLABORATION WITH REGEN THERAPEUTICS Proteome Sciences plc ('Proteome Sciences') is pleased to announce a ProteoSHOP collaboration funded by ReGen Therapeutics plc ('ReGen') for the characterization of Colostrinin, a proline-rich polypeptide complex derived from bovine colostrum, which ReGen are developing as a human and veterinary nutraceutical. ReGen also believes that the peptides within Colostrinin, or small molecular weight compounds based on them, may have potential as pharmaceutical agents for the treatment of Alzheimer's and other neurodegenerative diseases. Proteome Sciences will apply its ProteoSHOP proteomic technologies to the biochemical characterization and activity profiling of Colostrinin. This follows an earlier proteomic study for ReGen undertaken by Proteome Sciences to compare the expression of proteins from neuronal cells before and after treatment with Colostrinin. Financial details of the collaboration were not disclosed. Commenting on the announcement, Christopher Pearce, Chief Executive of Proteome Sciences said: 'We are delighted to be collaborating further with ReGen and helping them identify the bioactive components of Colostrinin. By combining our ProteoSHOP toolkit with the expertise we have already developed in Alzheimer's and other neurodegenerative diseases, Proteome Sciences is uniquely positioned to undertake this project'. For further information please contact: Proteome Sciences plc www.proteomics.com Christopher Pearce, Chief Executive Tel: +44 (0)1932 865065 Email: christopher.pearce@proteomics.com Public Relations for Proteome Sciences IKON Associates Adrian Shaw Tel: +44 (0)1483 535102 Mobile: +44 (0)797 9900733 Email: adrian@ikonassociates.com Notes to Editors: Proteome Sciences plc applies high sensitivity proteomics to identify and characterise differential protein expression in diseases for diagnostic, prognostic and therapeutic applications. It has to date developed sensitive blood assays for stroke, vCJD, BSE, solid organ transplant rejection and Alzheimer's disease. The main focus of its research currently addresses neurological, neurodegenerative, diabetes/obesity, oncology and cardiovascular conditions. In addition to its own proprietary biomarkers, Proteome Sciences has developed ProteoSHOP (Proteome Sciences High Output Proteomics), a toolbox that offers high sensitivity and high throughput gel and gel-free proprietary technologies for the identification of potential biomarkers and drug targets. These include specialisation in membrane proteins and protein phosphorylation. The Company has also developed a range of specialist reagents to improve the performance and quantitation of protein separation and characterisation with mass spectrometry, bioinformatics, statistics and pattern recognition. These include Sensitizer, PST, qPST and TMT. The process of commercialisation is being actively pursued across the portfolio of the Company's programmes and technologies and to date licensing deals have been signed for the commercialisation of tests for Stroke and TSEs. Proteome Sciences is headquartered in Cobham, Surrey in the UK and has laboratories at Kings College Hospital, London and in Frankfurt. It employs 40 full time scientists in addition to its corporate and business development staff. The Company is listed on the Alternative Investment Market. ENDS
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