Holding(s) in Company

For filings with the FSA include the annex                                     
                                                                               
For filings with issuer exclude the annex                                      

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                

1. Identity of the issuer or the underlying       Oxford Instruments plc       
issuer of existing shares to which voting                                      
rights are attached: ii                                                        

2 Reason for the notification (please tick the appropriate box or boxes):      

An acquisition or disposal of voting rights                                    
                                                                               
An acquisition or disposal of qualifying financial instruments which           
may result in the acquisition of shares already issued to which voting         
rights are attached                                                            
                                                                               
An acquisition or disposal of instruments with similar economic effect         
to qualifying financial instruments                                            
                                                                               
An event changing the breakdown of voting rights                         yes   
                                                                               
Other (please                                                                  
specify):                                                                      

3. Full name of person(s) subject to  Kames Capital                            
the notification obligation: iii                                               
                                                                               
4. Full name of shareholder(s) (if                                             
different from 3.):iv                                                          
                                                                               
5. Date of the transaction and date   3 January 2013                           
on which the threshold is crossed or                                           
reached: v                                                                     
                                                                               
6. Date on which issuer notified:     7 January 2013                           
                                                                               
7. Threshold(s) that is/are crossed   5%                                       
or reached: vi, vii                                                            

8. Notified details:
A: Voting rights attached to shares viii, ix

Class/type   Situation previous            Resulting situation after           
of            to the triggering                  the triggering                
shares           transaction                      transaction                  
                                                                               
                                                                               
if possible             Number                   Number          % of voting   
using         Number      of      Number           of             rights x     
the ISIN        of      Voting      of           voting                        
CODE          Shares    Rights    shares         rights                        
                                                                               
                                                                               
                                 Indirect  Direct xi Indirect  Direct  Indirect
                                                       xii                     
                                                                               
GB0006650450 2,821,014 2,821,014 1,802,062 1,802,062 922,306   3.17%    1.63%  

B: Qualifying Financial Instruments                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of financial Expiration     Exercise/      Number of voting   % of voting 
   instrument     date xiii  Conversion Period rights that may be    rights    
                                    xiv         acquired if the                
                                                 instrument is                 
                                                   exercised/                  
                                                   converted.                  
                                                                               
       n/a                                                                     

C: Financial Instruments with similar economic effect to Qualifying Financial  
Instruments xv, xvi                                                            
                                                                               
Resulting situation after the triggering transaction                           

   Type of     Exercise Expiration Exercise/  Number of voting    % of voting   
  financial     price   date xvii  Conversion rights instrument  rights xix, xx 
  instrument                         period       refers to                     
                                     xviii                                      
                                                                                
                                                                Nominal   Delta 
                                                                                
Contract for                                       96,646        0.17%      1   
Difference                                                                      

Total (A+B+C)                                                                  
                                                                               
        Number of voting rights               Percentage of voting rights      
                                                                               
               2,821,014                                 4.97%                 

9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable: xxi                 
                                                                               
Kames Capital:-                                                                
                                                                               
Kames Capital plc                                                              
Kames Capital Management Ltd                                                   
Kames Capital ICVC                                                             
Kames Capital VCIC                                                             

Proxy Voting:                                                                  
                                                                               
10. Name of the proxy holder:                        Kames Capital             
                                                                               
11. Number of voting rights proxy                                              
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                   

13. Additional information:                     Oxford Instruments plc         
                                                                               
14. Contact name:                                 Susan Johnson-Brett          
                                                                               
15. Contact telephone number:                        01865 393 324