Holding(s) in Company

Oxford Instruments plc has been notified that:-

1. Schroders plc now holds indirect voting rights over 5,983,118 ordinary
shares of 5p each, which represents 12.11% of the issued share capital of the
Company.

The Registered Holders of these voting rights are as follows:

Schroder Investment Management Limited                   5,657,397    11.45%
                                                                            
Schroder Investment Management North America               323,721     0.66%
Limited                                                                     
                                                                            
Schroder & Co Limited                                        2,000    0.004%

 2. Legal & General Group Plc now holds direct voting rights over 1,946,028
    ordinary shares of 5p, which represents 3.93% of the issued share capital
    of the Company.
   
The Registered Holders of these voting rights are as follows:

Legal & General Group Plc (Direct and Indirect) (Group)                     
                                                                            
Legal & General Investment Management (Holdings) Limited (LGIMH) (Direct and
Indirect)                                                                   
                                                                            
Legal & General Investment Management Limited (Indirect) (LGIM)             
                                                                            
Legal & General Group Plc (Direct) (L&G) (1,946,028 - 3.93% = LGAS, LGPL &  
PMC)                                                                        
                                                                            
Legal & General Investment Management (Holdings) Limited (Direct) (LGIMHD)  
(1,776,454 - 3.59% = PMC)                                                   
                                                                            
Legal & General Insurance Holdings Limited (Direct) (LGIH)                  
                                                                            
Legal & General Assurance (Pensions Management) Limited (PMC) (1,776,454 -  
3.59% = PMC)                                                                
                                                                            
Legal & General Assurance Society Limited (LGAS & LGPL)                     
                                                                            
Legal & General Pensions Limited (Direct) (LGPL)                            

29 January 2009

Susan Johnson-Brett

Company Secretary

Oxford Instruments plc

Tel: [phone]

Email: [e-mail]