Holding(s) in Company

Oxford Instruments plc has been notified today that Schroders plc now holds
indirect voting rights over 5,912,892 ordinary shares of 5p each, which
represents 11.97% of the issued share capital of the Company.

The Registered Holders of these voting rights are as follows:

Schroder Investment Management Limited                   5,604,897    11.34%
                                                                            
Schroder Investment Management North America               307,995     0.62%
Limited                                                                     
                                                                            

7 May 2009

Susan Johnson-Brett

Company Secretary

Oxford Instruments plc

Tel: [phone]

Email: [e-mail]