Holding(s) in Company

Oxford Instruments plc has been notified that:-

a) Schroders plc now has an interest and indirect holding in 5,757,542 Ordinary
Shares of 5p each which represents 11.672% of the issued share capital of the
Company. The number of voting rights is also 5,330,095.

The Registered Holders of these shares are as follows:

Schroder Investment Management Limited 5,431,799

Schroder Investment Management North America Limited 323,743

Schroder & Co Limited 2,000

b) The Hermes UK Small Companies Focus Fund now has an interest and indirect
holding in 4,818,516 Ordinary Shares of 5p each which, represents 9.768% of the
issued share capital of the Company. The number of voting rights is also
4,818,516.