Chairman's Statement

Surgical Innovations Group PLC 25 April 2000 CHAIRMAN'S REMARKS AT ANNUAL GENERAL MEETING 25 APRIL 2000 Since my Chairman's Statement with the Annual Report, issued just one month ago, there have been a number of significant changes at your Company. Firstly, my predecessor, Brian Long, who remained a non- executive director when he relinquished the chairmanship last December, has now resigned from the Board. Also, as part of the strategic review of the Company's activities that I announced in my Chairman's Statement, there have been further changes to the Board. Ian Lomas, by amicable agreement, has stepped down as Managing Director and, on behalf of the Board, I wish to thank Ian for his valuable contribution to the Company in its formative years and wish him every success for the future. The strategic review has indicated that, despite the continuing interest in and increasing demand for our blood products, there is likely to be a requirement for a further considerable investment of the Company's resources in the short term, before this division returns to profitability. Therefore, the Board has decided that the preferable route is to look for a strategic partner who can provide the necessary investment to develop its market area more speedily than we can. Also, as part of the strategic review, the Board believes that resources should be concentrated on Ion Product Solutions, the Division which offers design and manufacturing solutions to other healthcare companies, as well as dealing with the Company's own product developments. Therefore, Stuart Moran has been appointed to the Board as Technical Director. Given the innovative nature of the business it has become necessary to have technical representation on the main Board. Stuart has been with Surgical Innovations Limited, the operating Company, virtually since its inception and the Board believes his experience and knowledge will be of significant benefit as the Company moves forward. It is pleasing to report that we have an increasing royalty income stream from Genzyme, the US licensee of our Endoflex technology. Against this background we are waiting to examine other measures with a view to providing the Company with a stable and profitable base from which to expand. We are also looking to develop our UK distribution division that markets our own and third party products aimed primarily at the operating theatre. Sales have been slower than anticipated but we are confident that our efforts in this area will bear fruit in the near future. Our main area for encouragement is Ion Product Solutions. In this regard, we are delighted to announce the recent signing of a design and manufacturing contract with Genzyme France, in respect of a device for the laparoscopic deployment of Genzyme's anti-adhesion barrier, SEPRAFILM. Francois Cornu, President of Genzyme France, commented, 'We know we can rely on Ion to deliver innovative and quality solutions'. Current contracted business with Genzyme now stands at over 0.5 million pounds. Until a new Managing Director can be appointed, Graham Bowland, our Finance Director, together with Stuart Moran, will be sharing the responsibilities of the day-to- day running of the Company. In addition, Colin Glass, a non-executive Director, and myself will be devoting additional time to the Company. We both have extensive business experience, including within the healthcare industry, and have been involved with the Company from its early days. Also we have the continuing support of Getz Bros, an international medical distribution Company, through Ray Simkins, our other non-executive Director. In recognition of this additional involvement and as an incentive to the Directors, the Board has agreed to issue each Director with 1 million share options at a price of 5p. Your Board is confident that there is an exciting future for the Company following the current reorganisation. Finally, I would like to offer my grateful thanks to my colleagues, both past and present, and to all the staff who have put in so much hard work. DOUG LIVERSIDGE 25 APRIL 2000
UK 100