Notification of Transactions of Director/PDMR

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1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Clive Gavin Brown
2	Reason for the notification
a)	Position/status	Chief Technology Officer
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Exercise of vested share options in connection with the IPO of the Company.
c)	Price Volume Total	£0.13 234998 £30549.74
d)	Aggregated Price Aggregated volume Aggregated Total	£0.13 234998 £30549.74
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Clive Gavin Brown
2	Reason for the notification
a)	Position/status	Chief Technology Officer
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Sale of ordinary shares in the Company in connection with the IPO of the Company.
c)	Price Volume Total	£4.25 426064 £1810772.00
d)	Aggregated Price Aggregated volume Aggregated Total	£4.25 426064 £1810772.00
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Timothy Cowper
2	Reason for the notification
a)	Position/status	Chief Financial Officer
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Exercise of vested share options in connection with the IPO of the Company.
c.i)	Price Volume Total	£1.20 87164 £ 104596.80
c.ii)	Price Volume Total	£0.73 5000 £3650.00
d)	Aggregated Price Aggregated volume Aggregated Total	£1.175 92164 £108246.80
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Timothy Cowper
2	Reason for the notification
a)	Position/status	Chief Financial Officer
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Sale of ordinary shares in the Company in connection with the IPO of the Company.
c)	Price Volume Total	£4.25 112678 £478881.50
d)	Aggregated Price Aggregated volume Aggregated Total	£ 4.25 112678 £478881.50
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	James Willcocks
2	Reason for the notification
a)	Position/status	Chief Business Development Officer,
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Sale of ordinary shares in the Company in connection with the IPO of the Company.
c)	Price Volume Total	£4.25 368000 £1563999.94
d)	Aggregated Price Aggregated volume Aggregated Total	£4.25 368000 £1563999.94
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)

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Latest directors dealings

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Peter Vance Allen
2	Reason for the notification
a)	Position/status	Chair of the Board
b)	Initial/Amendment notification	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Oxford Nanopore Technologies PLC
b)	LEI	213800IRWQ2Q6M2CDW55
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares with a nominal value of £0.0001 each GB00BP6S8Z30
b)	Nature of the transaction	Exercise of vested share options in connection with the IPO of the Company.
c)	Price Volume Total	£0.07 36820 £2459.58
d)	Aggregated Price Aggregated volume Aggregated Total	£0.07 36820 £2459.58
e)	Date of the transaction	5 October 2021
f)	Place of the transaction	London Stock Exchange (XLON)