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3i Bioscience Inv (BSI)

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Monday 03 March, 2003

3i Bioscience Inv

Holding(s) in Company

3i Bioscience Investment Trust PLC
03 March 2003

                                  SCHEDULE 10

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES

1. Name of company

3i Bioscience Investment Trust plc

2. Name of shareholder having a major interest

Deutsche Bank AG

3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Deutsche Bank AG and its subsidiary companies

4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them
Registered holder                                            Number of shares

Deutsche Bank AG London branch                               2,720,458

5. Number of shares / amount of stock acquired

not known

6. Percentage of issued class

not known

7. Number of shares / amount of stock disposed

not known

8. Percentage of issued class

not known

9. Class of security

Ordinary shares of 25p each

10. Date of transaction

not known

11. Date company informed

28 February 2003

12. Total holding following this notification

2,720,458

13. Total percentage holding of issued class following this notification

6.08%

14. Any additional information

Part of this holding may relate to hedging arrangements for Deutsche Bank AG customer transactions.

15. Name of contact and telephone number for queries

Pandora Sharp - 020 7975 3228

16. Name and signature of authorised company official responsible for making
this notification

For and on behalf of 3i plc, Secretaries to 3i Bioscience Investment Trust plc

Date of notification

3 March 2003




                      This information is provided by RNS
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