AGM Statement

Fulcrum Pharma PLC
19 December 2005


For immediate release                                          19 December 2005

                               FULCRUM PHARMA PLC
                         ('the Group' or 'the Company')

                             ANNUAL GENERAL MEETING

Fulcrum Pharma plc (AIM: FUL), the drug development and strategic outsourcing
services company, today held its Annual General Meeting at which all of the
resolutions put to shareholders were duly passed.

Fulcrum's Chairman, Prof. Sir Charles George, said: 'Following our Annual
General Meeting today we are pleased to report that trading is in line with
expectations.'

For further information, please contact:

Fulcrum Pharma PLC                                           Tel: [phone]
Jon Court, Chief Executive

Buchanan Communications                                      Tel: [phone]
Mary-Jane Johnson




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