Issue of Shares

Stem Cell Sciences plc 13 April 2007 Stem Cell Sciences plc ("SCS" or "the Company") Issue of Shares Stem Cell Sciences plc, the global biotechnology company focused on the commercialisation of stem cells and stem cell technologies in research and cell-based therapies, has today issued 11,214,954 new Ordinary Shares to satisfy the placement of securities following its successful fundraising in Australia. From admission the new shares will rank pari passu in all respects with, and be identical to, the existing issued ordinary share capital of the Company. It is anticipated that the CHESS Depository Interests** will start trading on the Australian Stock Exchange ("ASX") on Monday 16 April 2007, with admission to AIM expected to commence at 8.00am GMT on Friday 13 April 2007. The Company's issued share capital consists of 33,516,149 ordinary shares of 1p each, with one voting right per share. There are no shares held in treasury. The total number of voting rights in the Company is therefore 33,516,149. The above figure of 33,516,149 may be used by shareholders as the denominator for the calculations by which they will determine if they are required to notify their interest in, or a change to their interest in, the Company, under the Disclosure and Transparency Rules. The Company raised AU$12 million (£4.94 million*) in a placement in Australia which was oversubscribed and received excellent support from both institutional and retail investors. * Exchange rate used is £1 = AU$2.43 ** CHESS Depositary Interests - The main difference between holding CDIs and Shares is that the holder of CDIs has beneficial ownership of the underlying Shares instead of legal title. CHESS Depositary Nominees Pty Ltd, a wholly owned subsidiary of ASX, holds the legal title to the underlying Shares. Holders of CDIs will have the same economic benefits of holding the underlying Shares. In particular, holders of CDIs will be able to transfer and settle transactions electronically on the ASX. - Ends - For further information, please contact: Stem Cell Sciences Peter Mountford, President and CEO 0131 662 9829 Hugh Ilyine, Vice President and Chief Operating Officer Sue Furber, Director of Finance & Company Secretary Weber Shandwick Financial Louise Robson/James White 020 7067 0700 Notes to Editors Stem Cell Sciences plc (AIM: STEM, ASX: STC) is a global biotechnology company, established in Melbourne, Australia in 1994, providing products in the burgeoning stem cell research and drug discovery markets, in addition to the targeted development of cell-based therapies for neurodegenerative disease and injury. The Company has established a leading intellectual property (IP) and technology portfolio that enables the commercial application of stem cells in drug discovery, providing the Company with early-stage revenue streams and technology development for at scale cell production of SCS cell-based therapeutics. SCS principal focus is in neurological disease. Revenues in the neurotech market, including pharmaceuticals, devices and diagnostics, grew 10% in 2005 to US$110 billion (Neurotech Insights, Volume 2/3 April 30 2006). SCS operates as a group of independent operations with offices and laboratories in Edinburgh and Cambridge, UK, Kobe, Japan, Melbourne, Australia and San Francisco, USA (office only). Each SCS facility is affiliated with an academic centre of excellence. These include the Institute of Stem Cell Research (ISCR), Edinburgh, UK, RIKEN Centre for Development Biology, Kobe, Japan and the Australian Stem Cell Centre, Melbourne, Australia. SCS has four business units, each dedicated to different aspects of the stem cell business opportunity. SC Proven(R) provides cell culture media (liquid formulations) and reagents that enable the growth and differentiation of stem cells. The first SC Proven(R) product, "ESGRO CompleteTM", a cell culture medium capable of consistent growth of mouse embryonic stem cells without serum or feeder cell support was launched in February 2006. This was followed by "HEScGROTM", the first animal-component free cell culture medium to enable improved growth of human embryonic stem cells, in January 2007. These products are manufactured and distributed by Chemicon International, now part of Millipore Corporation. SC Licensing licenses SCS proprietary technologies, such as Internal Ribosome Entry Site (IRES), Stem Cell Selection, hMADS (human adipose derived stem cells) and Neural Stem Cell Technology for application in laboratory-based research and discovery. SCS has licensed technology to major pharmaceutical and biotechnology companies including Merck & Co, Pfizer, Sanofi Aventis, GSK, Deltagen Inc and Lexicon Genetics Inc and others. SC Services provides specialised stem cell production for basic research and drug discovery, including high-throughput applications through an automated cell production facility in Cambridge UK. The services offered include the creation of specific cell lines for a customer, the modification of existing cell lines so that they can be grown in serum free SC Proven(R) media, and the supply of cells for drug screening in multi-well plate format. SC Therapies' goal is to develop safe and effective cell-based therapies for currently incurable diseases. Initial research is being directed to developing and characterising cell lines of potential therapeutic value in the treatment of spinal injury, Parkinson's disease, eye disease, epilepsy and Duchenne Muscular Dystrophy (DMD). Programmes to test SCS' proprietary stem cells in animal models of spinal cord injury have been initiated in a number of disease models and preclinical studies for the treatment of Duchenne Muscular Dystrophy are anticipated in 2007-8. For further information on the company please visit: www.stemcellsciences.com This information is provided by RNS The company news service from the London Stock Exchange

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