ASX Share Offer Closes

Stem Cell Sciences plc 03 April 2007 3 April, 2007 Stem Cell Sciences Closes Share Offer Over Subscribed Stem Cell Sciences plc (LSE:STEM), the global biotechnology company focused on the commercialisation of stem cells and stem cell technologies in research and cell-based therapies, is pleased to announce that it has closed its share offer ahead of plans following strong demand from investors. The offer has been heavily oversubscribed. Stem Cell Sciences has raised AU$12 million (£4.94 million*) through the issue of 11.2 million shares in the form of CHESS Depositary Interests (CDIs)** at $1.07 (£0.44). The Company is expected to list on the Australian Stock Exchange on 12 April, using the code STC, with a post-listing market capitalisation of AU$49.6 million (£20.41 million), based on SCS's closing price in the UK on April 2. Stem Cell Sciences' shares will continue to be traded on the Alternative Investment Market of the London Stock Exchange. "We are delighted with the response to the share offering and welcome the support from both existing and new shareholders in the company, including several notable institutional investment groups," said Dr Peter Mountford, CEO of Stem Cell Sciences. "As the listing on the ASX is completed, we look forward to continuing to build our revenue generating business units and expand our activities in the USA while conducting early stage testing on our stem cell therapy pipeline. We are well positioned to take advantage of the expanding markets in the stem cell field in line with the objectives set out in the Prospectus," he continued. - Ends - * Exchange rate used is £1 = AU$2.43 ** CHESS Depositary Interests - The main difference between holding CDIs and Shares is that the holder of CDIs has beneficial ownership of the underlying Shares instead of legal title. CHESS Depositary Nominees Pty Ltd, a wholly owned subsidiary of ASX, holds the legal title to the underlying Shares. Holders of CDIs will have the same economic benefits of holding the underlying Shares. In particular, holders of CDIs will be able to transfer and settle transactions electronically on the ASX. Except for historical information, this news release may contain forward-looking statements that reflect the Company's current expectation regarding future events. These forward looking statements involve risk and uncertainties, which may cause but are not limited to, changing market conditions, the successful and timely completion of clinical studies, the establishment of corporate alliances, the impact of competitive products and pricing, new product development, uncertainties related to the regulatory approval process, and other risks detailed from time to time in the Company's ongoing reporting. For further information, please contact: Stem Cell Sciences Peter Mountford, President and CEO 0131 662 9829 Hugh Ilyine, Vice President and Chief Operating Officer Sue Furber, Director of Finance & Company Secretary Weber Shandwick Financial Louise Robson 020 7067 0700 James White Notes to Editors Stem Cell Sciences plc (SCS, AIM: STEM) is a global biotechnology company, established in Melbourne, Australia in 1994, providing products in the burgeoning stem cell research and drug discovery markets, in addition to the targeted development of cell-based therapies for neurodegenerative disease and injury. The Company has established a leading intellectual property (IP) and technology portfolio that enables the commercial application of stem cells in drug discovery, providing the Company with early-stage revenue streams and technology development for at scale cell production of SCS cell-based therapeutics. SCS principal focus is in neurological disease. Revenues in the neurotech market, including pharmaceuticals, devices and diagnostics, grew 10% in 2005 to US$110 billion (Neurotech Insights, Volume 2/3 April 30 2006). SCS operates as a group of independent operations with offices and laboratories in Edinburgh and Cambridge, UK, Kobe, Japan, Melbourne, Australia and San Francisco, USA (office only). Each SCS facility is affiliated with an academic centre of excellence. These include the Institute of Stem Cell Research (ISCR), Edinburgh, UK, RIKEN Centre for Development Biology, Kobe, Japan and the Australian Stem Cell Centre, Melbourne, Australia. SCS has four business units, each dedicated to different aspects of the stem cell business opportunity. SC Proven(R) provides cell culture media (liquid formulations) and reagents that enable the growth and differentiation of stem cells. The first SC Proven(R) product, "ESGRO CompleteTM", a cell culture medium capable of consistent growth of mouse embryonic stem cells without serum or feeder cell support was launched in February 2006. This was followed by "HEScGROTM", the first animal-component free cell culture medium to enable improved growth of human embryonic stem cells, in January 2007. These products are manufactured and distributed by Chemicon International, now part of Millipore Corporation. SC Licensing licenses SCS proprietary technologies, such as Internal Ribosome Entry Site (IRES), Stem Cell Selection, hMADS (human adipose derived stem cells) and Neural Stem Cell Technology for application in laboratory-based research and discovery. SCS has licensed technology to major pharmaceutical and biotechnology companies including Merck & Co, Pfizer, Sanofi Aventis, GSK, Deltagen Inc and Lexicon Genetics Inc and others. SC Services provides specialised stem cell production for basic research and drug discovery, including high-throughput applications through an automated cell production facility in Cambridge UK. The services offered include the creation of specific cell lines for a customer, the modification of existing cell lines so that they can be grown in serum free SC Proven(R) media, and the supply of cells for drug screening in multi-well plate format. SC Therapies' goal is to develop safe and effective cell-based therapies for currently incurable diseases. Initial research is being directed to developing and characterising cell lines of potential therapeutic value in the treatment of spinal injury, Parkinson's disease, eye disease, epilepsy and Duchenne Muscular Dystrophy (DMD). Programmes to test SCS' proprietary stem cells in animal models of spinal cord injury have been initiated in a number of disease models and preclinical studies for the treatment of Duchenne Muscular Dystrophy are anticipated in 2007-8. For further information on the company please visit: www.stemcellsciences.com This information is provided by RNS The company news service from the London Stock Exchange

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