Holding(s) in Company

Smith & Nephew Plc
02 August 2005

                   NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Name of company



Smith & Nephew plc



2. Name of shareholder having a major interest



Barclays plc



3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18



Non-beneficial interest



4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them



Barclays Capital Nominees Limited                  1,786,178

Barclays Trust Co & Others                         7,705

Barclays Trust Co E99                              36

Barclays Trust Co R69                              11,920

Chase Nominees Limited                             516,711

Gerrard Nominees Limited                           106,805

Greig Middleton Nominees Limited                   725,595

Greig Middleton Nominees Limited                   83,050

Investors Bank and Trust Co.                       1,822,057

Investors Bank and Trust Co.                       26,702

Investors Bank and Trust Co.                       13,652

Investors Bank and Trust Co.                       183,430

Investors Bank and Trust Co.                       179,950

Investors Bank and Trust Co.                       170,324

Investors Bank and Trust Co.                       50,148

Investors Bank and Trust Co.                       252,423

Investors Bank and Trust Co.                       1,088,628

Investors Bank and Trust Co.                       212,486

Investors Bank and Trust Co.                       9,915

Investors Bank and Trust Co.                       283,518

Investors Bank and Trust Co.                       4,769,060

JP Morgan (BGI Custody)                            289,097

JP Morgan (BGI Custody)                            55,799

JP Morgan (BGI Custody)                            517,519

JP Morgan (BGI Custody)                            113,241

JP Morgan (BGI Custody)                            10,019,295

JP Morgan (BGI Custody)                            15,268

JP Morgan (BGI Custody)                            38,843

JP Morgan Chase Bank                               60,469

JP Morgan Chase Bank                               9,587

JP Morgan Chase Bank                               788

JP Morgan Chase Bank                               161,182

JP Morgan Chase Bank                               182,061

JP Morgan Chase Bank                               125,539

JP Morgan Chase Bank                               495,553

JP Morgan Chase Bank                               99,632

JP Morgan Chase Bank                               8,045

JP Morgan Chase Bank                               9,258

JP Morgan Chase Bank                               26,806

JP Morgan Chase Bank                               131,787

JP Morgan Chase Bank                               38,362

JP Morgan Chase Bank                               28,881

Mellon Trust - Boston & SF                         130,277

Mitsubishi Trust International                     6,073

R C Greig Nominees Limited                         3,604,046

R C Greig Nominees Limited                         1,436,699

R C Greig Nominees Limited                         280,892

R C Greig Nominees Limited                         186,261

R C Greig Nominees Limited GP1                     425,605

R C Greig Nominees Limited SA1                     334,125

Reflex Nominees Limited                            1,500

State Street                                       16,123

State Street Boston                                80,662

State Street Boston                                610,405

Zeban Nominees Limited                             84,248





5. Number of shares / amount of stock acquired



31,924,221



6. Percentage of issued class



3.40%



7. Number of shares / amount of stock disposed







8. Percentage of issued class







9. Class of security



Ordinary Shares of 12 2/9p



10. Date of transaction






11. Date company informed



02.08.2005



12. Total holding following this notification



31,924,221



13. Total percentage holding of issued class following this notification



3.40%



14. Any additional information







15. Name of contact and telephone number for queries



Kate Cummins - Company Secretarial Assistant

020 7960 2251



16. Name and signature of authorised company official responsible for making
this notification



Kate Cummins - Company Secretarial Assistant



Date of notification



02.08.2005



The FSA does not give any express or implied warranty as to the accuracy of this
document or material and does not accept any liability for error or omission.
The FSA is not liable for any damages (including, without limitation, damages
for loss of business or loss of profits) arising in contract, tort or otherwise
from the use of or inability to use this document, or any material contained in
it, or from any action or decision taken as a result of using this document or
any such material.




                      This information is provided by RNS
            The company news service from the London Stock Exchange               EPSEFE