Holding(s) in Company

Smith & Nephew Plc
29 November 2005


                   NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Name of company

Smith & Nephew plc


2. Name of shareholder having a major interest

Deutsche Bank AG


3. Please state whether notification indicates that it is in respect of holding
of the shareholder named in 2 above or in respect of a non-beneficial interest
or in the case of an individual holder if it is a holding of that person's
spouse or children under the age of 18

Deutsche Bank AG


4. Name of the registered holder(s) and, if more than one holder, the number of
shares held by each of them

Deutsche Bank AG


5. Number of shares / amount of stock acquired

Not known


6. Percentage of issued class

Not known


7. Number of shares / amount of stock disposed

...............................................................


8. Percentage of issued class

...............................................................


9. Class of security

Ordinary shares of 12 2/9 pence


10. Date of transaction

...............................................................


11. Date company informed

28 November 2005


12. Total holding following this notification

31,290,456


13. Total percentage holding of issued class following this notification

3.33


14. Any additional information

...............................................................


15. Name of contact and telephone number for queries

Phil Higgins


16. Name and signature of authorised company official responsible for making
this notification

Phil Higgins, Assistant Company Secretary


Date of notification

29 November 2005


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