Re Agreement

Aortech International PLC 18 December 2001 AORTECH INTERNATIONAL PLC Supply agreement for next generation heart valve AorTech International plc ('AorTech' or the 'Company'), the Scottish-based developer and manufacturer of cardio-vascular devices, announces that it has concluded a long term supply agreement with Invibio Limited, a subsidiary of Victrex plc for the supply of PEEK-OPTIMAO. This material is used as a frame for the synthetic tri-leaflet heart valve. Eddie McDaid, Chief Executive of AorTech stated that: 'Following our successful development work with the new tri-leaflet heart valve we will utilise PEEK-OPTIMA in conjunction with our own Elast-Eon material. The new tri-leaflet heart valve is currently going through the testing required for regulatory purposes both in the US and Europe and in-vivo trials have commenced in Minneapolis, USA. 'Concluding this long-term supply agreement with Invibio ensures continuity of supply of PEEK-OPTIMA both during clinical trials in patients and thereafter when we enter manufacturing. Michael Callahan, Managing Director of Invibio commented: 'Invibio is pleased to be involved in providing PEEK-OPTIMA for use in this exciting project and to have our material specified as part of AorTech's next generation heart valve. With AorTech now planning for clinical trials in patients we are pleased to have concluded a supply arrangement which will allow for the full commercialisation of the new heart valve.' 18th December 2001 ENQUIRIES: AorTech International plc Tel: 01698 746 699 Eddie McDaid, Chief Executive College Hill Tel: 020 7457 2020 Michael Padley Nicholas Nelson
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