Holding(s) in Company

Aortech International PLC
24 August 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

AorTech International plc


2. Reason for the notification (please state Yes/No): ( )

An acquisition or disposal of voting rights: (Yes )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: ( )

An event changing the breakdown of voting rights: ( )

Other (please specify): ( )



3. Full name of person(s) subject to the notification obligation (iii):

GAM International Management Limited

4. Full name of shareholder(s) (if different from 3.) (iv):



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

20 August 2007

6. Date on which issuer notified:


22 August 2007


7. Threshold(s) that is/are crossed or reached:

5%


8. Notified details:



A: Voting rights attached to shares

Class/type of shares if possible using Situation previous to the Triggering transaction
the ISIN CODE                                                (vi)
                                        Number of shares  Number of voting Rights (viii)
GB0033360586                                           0                               0


Resulting situation after the triggering transaction (vii) Less than 3%

Class/type of shares    Number of shares    Number of voting rights     % of voting rights
if possible using the                                 (ix)
ISIN CODE
                                    Direct  Direct (x)  Indirect (xi)       Direct  Indirect
GB0033360586                       196,077     196,077                       5.15%

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of        Expiration Date      Exercise/Conversion      Number of voting rights   % of voting rights
financial      (xiii)               Period/Date (xiv)        that may be acquired if
instrument                                                   the instrument is
                                                             exercised/ converted.

N/A                             N/A                      N/A                       N/A                  N/A


Total (A+B)
    Number of voting rights     % of voting rights
                    196,007                  5.15%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):

GAM International Limited is the discretionary investment manger for the
following:

+-----------------------------+--------------------+-------------------------+-------------------+
|Fund Name                    |Last Trade Date     |Nominal                  |% of Issue         |
+-----------------------------+--------------------+-------------------------+-------------------+
|GAM Star UK Dynamic Equity   |20 August 2007      |61,790.00                |1.622              |
|Investments                  |                    |                         |                   |
|                             |                    |                         |                   |
|                             |                    |                         |                   |
+-----------------------------+--------------------+-------------------------+-------------------+
|GAM UK Equity Hedge          |20 August 2007      |134,287.00               |3.524              |
|Investments Inc.             |                    |                         |                   |
+-----------------------------+--------------------+-------------------------+-------------------+


Period of Interest 12 August 2007 to 22 August 2007
Security AorTech International plc GBP2.50
ISIN GB0033360586
SEDOL 3336058
Uptix Code 3336058
Number of shares in issue 3,810,278.00


Proxy Voting:

10. Name of the proxy holder:


Institutional Shareholder Services


11. Number of voting rights proxy holder will cease to hold:


n/a


12. Date on which proxy holder will cease to hold voting rights:


n/a


13. Additional information:


n/a


14. Contact name:


n/a


15. Contact number:


n/a


Annex to Notification Of Major Interests In Shares (xvi)


A: Identity of the person or legal entity subject to the notification obligation


Full name (including legal form for legal entities):

GAM International Management Limited

Contact address (registered office for legal entities):

12 St James's Place, London SW1A 2NX

Phone number:

020 7917 2356

Other useful information (at least legal representative for legal persons):



B: Identity of the notifier, if applicable (xvii)


Full name:

Barbara Hall

Contact address:

As above

Phone number:

As above

Other useful information (e.g. functional relationship with the person or legal
entity subject to the notification obligation)

n/a




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