Holding(s) in Company

Aortech International PLC 23 August 2007 TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached (ii): AorTech International plc 2. Reason for the notification (please state Yes/No): ( ) An acquisition or disposal of voting rights: (Yes ) An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify): ( ) 3. Full name of person(s) subject to the notification obligation (iii): Deutsche Bank AG 4. Full name of shareholder(s) (if different from 3.) (iv): Deutsche Bank AG Tilney Group Ltd 5. Date of the transaction (and date on which the threshold is crossed or reached if different) (v): 21 August 2007 6. Date on which issuer notified: 22 August 2007 7. Threshold(s) that is/are crossed or reached: 6% 8. Notified details: A: Voting rights attached to shares Class/type of shares Situation previous to the Triggering transaction if possible using (vi) the ISIN CODE Number of shares Number of voting Rights (viii) GB0033360586 199,000 199,358 Resulting situation after the triggering transaction (vii) Class/type of Number of Number of voting % of voting rights shares if shares rights (ix) possible using the ISIN CODE Direct Direct Indirect Direct Indirect (x) (xi) GB0033360586 318,040 318,040 358 6.61 0.01 B: Financial Instruments Resulting situation after the triggering transaction (xii) Type of Expiration Date Exercise/Conversion Number of voting % of voting financial (xiii) Period/Date (xiv) rights that may be rights instrument acquired if the instrument is exercised/ converted. N/A N/A N/A N/A N/A Total (A+B) Number of voting rights % of voting rights 318,398 6.62 9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable (xv): Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: David Lindsay/Andrew Anderson 15. Contact number: +00 44 207 545 8533/8532 This information is provided by RNS The company news service from the London Stock Exchange
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