Holding(s) in Company

Aortech International PLC
23 August 2007


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES


1. Identity of the issuer or the underlying issuer of existing shares to which
   voting rights are attached (ii):

   AorTech International plc

2. Reason for the notification (please state Yes/No): ( )

   An acquisition or disposal of voting rights: (Yes )
   An acquisition or disposal of financial instruments which may result in the
   acquisition of shares already issued to which voting rights are attached: ( )
   An event changing the breakdown of voting rights: ( )
   Other (please specify): ( )

3. Full name of person(s) subject to the notification obligation (iii):

   Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):

   Credit Agricole Cheuvreux International Ltd

5. Date of the transaction (and date on which the threshold is crossed or
   reached if different) (v):

   21 August 2007

6. Date on which issuer notified:

   23 August 2007

7. Threshold(s) that is/are crossed or reached:

   Holding after transaction went through percentage threshold

8. Notified details:


A: Voting rights attached to shares

Class/type of shares Situation previous to the Triggering transaction
if possible using                          (vi)
the ISIN CODE
                      Number of shares  Number of voting Rights (viii)
GB0033360586                   136,000                         136,000


Resulting situation after the triggering transaction (vii) Less than 3%

Class/type of       Number of      Number of voting    % of voting rights
shares if            shares           rights (ix)
possible using
the ISIN CODE
                          Direct    Direct    Indirect     Direct Indirect
                                       (x)        (xi)
GB0033360586

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of     Expiration Date  Exercise/Conversion Number of voting     % of voting
financial   (xiii)           Period/Date (xiv)   rights that may be   rights
instrument                                       acquired if the
                                                 instrument is
                                                 exercised/
                                                 converted.
N/A          N/A             N/A                 N/A                  N/A


Total (A+B)
 Number of voting rights  % of voting rights



9. Chain of controlled undertakings through which the voting rights and/or the
   financial instruments are effectively held, if applicable (xv):

   SAS Rue La Boetie
   Credit Agricole SA
   Calyon SA
   Credit Agricole Cheuvreux SA Less than 3%

Proxy Voting:

10. Name of the proxy holder:


11. Number of voting rights proxy holder will cease to hold:


12. Date on which proxy holder will cease to hold voting rights:


13. Additional information:


14. Contact name:

    Anne McLeod
    Administrators Secretaries to Bluehone Investors LLP

15. Contact number:

    020 7214 6518




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