Holding(s) in Company

Aortech International PLC
13 February 2008


TR-1(i): NOTIFICATION OF MAJOR INTERESTS IN SHARES



1. Identity of the issuer or the underlying issuer of existing shares to which
voting rights are attached (ii):

AorTech International plc



2. Reason for the notification (please state Yes/No): (    )

An acquisition or disposal of voting rights: (Yes )

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached: (    )

An event changing the breakdown of voting rights: (    )

     Other (please specify): (   )





3. Full name of person(s) subject to the notification obligation (iii):

    Credit Agricole Cheuvreux International Ltd

4. Full name of shareholder(s) (if different from 3.) (iv):



Credit Agricole Cheuvreux International Ltd



5. Date of the transaction (and date on which the threshold is crossed or
reached if different) (v):

     8 February 2008

6. Date on which issuer notified:



12 February 2008



7. Threshold(s) that is/are crossed or reached:


     8%


8. Notified details:





A: Voting rights attached to shares


Class/type of shares if possible                    Situation previous to the Triggering transaction (vi)
using the ISIN CODE
                                                             Number of shares             Number of voting Rights (viii)
GB0033360586                                                          427,500                                    427,500



Resulting situation after the triggering transaction (vii)        Less than 3%


Class/type of shares if          Number of shares        Number of voting rights (ix)       % of voting rights
possible using the ISIN CODE
                                                Direct     Direct (x)     Indirect (xi)          Direct    Indirect
GB0033360586                                   372,500        372,500                 -           7.71%           -

B: Financial Instruments

Resulting situation after the triggering transaction (xii)
Type of          Expiration Date (xiii)  Exercise/Conversion Period/ Number of voting rights that  % of voting rights
financial                                Date (xiv)                  may be acquired if the
instrument                                                           instrument is exercised/
                                                                     converted.
N/A                                  N/A                         N/A                           N/A                    
N/A



Total (A+B)
Number of voting rights                   % of voting rights
372,500                                   7.71%



9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable (xv):

SAS Rue La Boetie
Credit Agricole SA
Calyon SA
Credit Agricole Cheuvreux SA    372,500 (7.71%)



Proxy Voting:

10. Name of the proxy holder:



11. Number of voting rights proxy holder will cease to hold:



12. Date on which proxy holder will cease to hold voting rights:



13. Additional information:



14. Contact name:



Gabrielle Burne



15. Contact number:



020 7214 6037




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